SCHEMBL5161585

SCHEMBL5161585

O=S(=O)(c1ccc(Cl)cc1)c1ccccc1-c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 3/20 0.54
PTGS1 P23219 1/20 0.54
ALDH1A1 P00352 2/20 0.52
CYP3A4 P08684 2/20 0.52
MAPK1 P28482 1/20 0.52
NAMPT P43490 2/20 0.50
NPSR1 Q6W5P4 3/20 0.48
KDM4E B2RXH2 2/20 0.48
POLB P06746 1/20 0.48
LMNA P02545 2/20 0.48
KMT2A Q03164 2/20 0.48
MAPT P10636 1/20 0.48
NFKB1 P19838 1/20 0.48
NFKB2 Q00653 1/20 0.48
RELA Q04206 1/20 0.48
CNR2 P34972 1/20 0.47
KIF18A Q8NI77 1/20 0.46
CYP2C19 P33261 1/20 0.46
HSD11B1 P28845 1/20 0.46
AKR1B1 P15121 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7871346 0.93 PTGS2 (0.56) PTGS2PTGS1ALDH1A1CYP3A4MAPK1
SCHEMBL7643603 0.93 PTGS2 (0.54) PTGS2PTGS1ALDH1A1CYP3A4MAPK1
SCHEMBL2947083 0.89 ALDH1A1 (0.60) PTGS2PTGS1ALDH1A1CYP3A4MAPK1
SCHEMBL7871344 0.87 PTGS2 (0.49) PTGS2PTGS1ALDH1A1CYP3A4MAPK1
SCHEMBL2947086 0.87 PTGS2 (0.49) PTGS2PTGS1ALDH1A1CYP3A4MAPK1
SCHEMBL9242466 0.87 HTR6 (0.55) PTGS2NAMPTPOLBKMT2AHSD11B1
SCHEMBL2019763 0.86 KIF18A (0.55) PTGS2PTGS1ALDH1A1CYP3A4MAPK1
SCHEMBL250146 0.85 PTGS2 (0.56) PTGS2PTGS1ALDH1A1CYP3A4MAPK1
SCHEMBL8844836 0.83 HTR6 (0.55) PTGS2NAMPTNPSR1POLBKMT2A
SCHEMBL10869745 0.82 ALDH1A1 (0.68) PTGS2PTGS1ALDH1A1CYP3A4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107903396-A More sulfuryl sulfonated polyether sulfones of ehter bond bridge joint and preparation method and application 黑泰(上海)材料科技有限公司 2018-04-13 CN claimed
CN-107602860-A More sulfuryl biphenyl type sulphonation polyether sulfones and preparation method and application 黑泰(上海)材料科技有限公司 2018-01-19 CN claimed
CN-114437353-B Method for producing aromatic polysulfone 住友化学株式会社 2024-07-16 CN disclosed
CN-116997620-A Powder primer composition 大金工业株式会社 2023-11-03 CN disclosed
CN-110352272-B Non-woven fabric 住友化学株式会社 2023-01-06 CN disclosed
CN-110382761-B Method for producing nonwoven fabric 住友化学株式会社 2022-05-10 CN disclosed
CN-109890871-B Method for producing aromatic polysulfone 住友化学株式会社 2022-05-10 CN disclosed
CN-114437353-A Method for producing aromatic polysulfone 住友化学株式会社 2022-05-06 CN disclosed
CN-110088171-B Continuous polymerization apparatus and method for continuously producing polymer 株式会社吴羽 2022-03-04 CN disclosed
CN-108299642-B Method for preparing polyarylether and use thereof in membrane preparation 费森尤斯医疗保健集团 2022-02-18 CN disclosed
CN-108430613-B Zwitterionic sulfone polymer blend and hollow fiber membranes 思拓凡瑞典有限公司 2022-02-11 CN disclosed
EP-1275164-A2 ION EXCHANGE MATERIALS VICTREX MANUFACTURING LIMITED (GB) 2003-01-15 EP disclosed
CN-1387553-A Variable temp. curable composition CYTEC TECH CORP (US) 2002-12-25 CN disclosed
EP-1265951-A2 ION-EXCHANGE MATERIALS VICTREX MANUFACTURING LIMITED (GB) 2002-12-18 EP disclosed
WO-2002075835-A2 POLYMER ELECTROLYTE MEMBRANE FUEL CELL VICTREX MANUFACTURING LIMITED (GB) 2002-09-26 WO disclosed
WO-2001070857-A2 ION-EXCHANGE MATERIALS VICTREX MANUFACTURING LIMITED (GB) 2001-09-27 WO disclosed
WO-2001071839-A2 ION EXCHANGE MATERIALS VICTREX MANUFACTURING LIMITED (GB) 2001-09-27 WO disclosed
EP-0235885-B1 POLYMER COMPOSITION ICI PLC (GB) 1992-08-12 EP disclosed
EP-0235885-A1 Polymer composition IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1987-09-09 EP disclosed
US-3939119-A Aromatic polyether-polythioether-polysulfone thermoplastics UNIROYAL, INC. (US) 1976-02-17 US disclosed