Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 7/20 | 0.49 |
| ▸ | RECQL | P46063 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | GSK3B | P49841 | 2/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28003830 | 0.78 | RECQL (0.50) | HSD11B1RECQLMAPK1MAPTTDP1 | |
| SCHEMBL29236675 | 0.78 | HSD11B1 (0.73) | HSD11B1RECQLMAPK1MEN1HPGD | |
| SCHEMBL7149069 | 0.78 | MAPK1 (0.54) | HSD11B1RECQLMAPK1MAPTTDP1 | |
| SCHEMBL260911 | 0.78 | ALDH1A1 (0.56) | HSD11B1RECQLMAPK1MAPTTDP1 | |
| SCHEMBL1516246 | 0.77 | MAPK1 (0.58) | HSD11B1RECQLMAPK1MAPTTDP1 | |
| SCHEMBL28538199 | 0.77 | RECQL (0.49) | HSD11B1RECQLMAPK1MAPTTDP1 | |
| SCHEMBL137832 | 0.75 | MAPK1 (0.56) | HSD11B1RECQLMAPK1MAPTTDP1 | |
| SCHEMBL7868384 | 0.74 | MAPK1 (0.54) | HSD11B1RECQLMAPK1MAPTTDP1 | |
| SCHEMBL2188285 | 0.74 | MAPT (0.54) | HSD11B1RECQLMAPK1MAPTTDP1 | |
| SCHEMBL544367 | 0.74 | MAPK1 (0.54) | HSD11B1RECQLMAPK1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105399649-A | Synthetic method for 2-difluoromethylsulfonylacetophenone | UNIV CHANGZHOU | 2016-03-16 | — | — | CN | disclosed |
| CN-105399649-A | Synthetic method for 2-difluoromethylsulfonylacetophenone | UNIV CHANGZHOU | 2016-03-16 | — | — | CN | disclosed |