SCHEMBL282835

SCHEMBL282835

CC(C)c1cc(Br)ccc1O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 3/20 0.58
GABRB1 P18505 2/20 0.58
ALOX15 P16050 3/20 0.50
GABRB2 P47870 2/20 0.48
HPGD P15428 5/20 0.45
THRA P10827 3/20 0.44
THRB P10828 3/20 0.44
LMNA P02545 4/20 0.43
SLC6A2 P23975 2/20 0.43
HTR2B P41595 2/20 0.43
CYP1A2 P05177 2/20 0.43
CES2 O00748 1/20 0.43
GALR3 O60755 1/20 0.43
TRPA1 O75762 1/20 0.43
CHRM1 P11229 1/20 0.43
ADRA1A P35348 1/20 0.43
CYP2C9 P11712 1/20 0.43
CASP1 P29466 1/20 0.43
CYP2C19 P33261 1/20 0.43
HSP90AA1 P07900 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31182212 1.00 GABRA1 (0.58) GABRA1GABRB1ALOX15GABRB2HPGD
Formaldehyde SCHEMBL27866505 0.94 GABRA1 (0.52) GABRA1GABRB1ALOX15GABRB2HPGD
SCHEMBL23037481 0.89 GABRA1 (0.47) GABRA1GABRB1ALOX15GABRB2HPGD
SCHEMBL6529715 0.86 GABRA1 (0.44) GABRA1GABRB1ALOX15GABRB2HPGD
SCHEMBL2984801 0.84 ALOX15 (0.48) GABRA1GABRB1ALOX15GABRB2HPGD
SCHEMBL20855720 0.83 ALOX15 (0.46) GABRA1GABRB1ALOX15HPGDLMNA
SCHEMBL20855723 0.83 ALOX15 (0.46) GABRA1GABRB1ALOX15HPGDLMNA
SCHEMBL6273718 0.83 ALOX15 (0.46) GABRA1GABRB1ALOX15GABRB2HPGD
SCHEMBL4912678 0.82 LMNA (0.59) GABRA1GABRB1ALOX15GABRB2HPGD
SCHEMBL3083574 0.81 ALOX15 (0.45) GABRA1GABRB1ALOX15HPGDLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 180 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122037020-A Supported catalyst, preparation method thereof and application thereof in olefin polymerization 中国石油化工股份有限公司 2026-05-15 CN claimed
CN-119613233-A Eutectic compound, preparation method and application thereof 上海科胜药物研发有限公司 2025-03-14 CN claimed
CN-112423756-B New process for the synthesis of phenoxy diaminopyrimidine compounds 默沙东有限责任公司 2024-08-13 CN claimed
CN-115894554-A Preparation method of phosphonic acid compound 烟台药物研究所 2023-04-04 CN claimed
US-11584724-B2 Process for synthesis of a phenoxy diaminopyrimidine compound MERCK SHARP & DOHME LLC (US) 2023-02-21 US claimed
US-20210122717-A1 NOVEL PROCESS FOR SYNTHESIS OF A PHENOXY DIAMINOPYRIMIDINE COMPOUND MERCK SHARP & DOHME CORP. (US) 2021-04-29 US claimed
EP-3784242-A1 NOVEL PROCESS FOR SYNTHESIS OF A PHENOXY DIAMINOPYRIMIDINE COMPOUND Merck Sharp&Dohme Corp. (US) 2021-03-03 EP claimed
CN-112423756-A Novel process for the synthesis of phenoxydiaminopyrimidine compounds 默沙东公司 2021-02-26 CN claimed
JP-6001746-A None JP disclosed
CN-122037020-A Supported catalyst, preparation method thereof and application thereof in olefin polymerization 中国石油化工股份有限公司 2026-05-15 CN disclosed
US-20260078117-A1 COMPOUNDS AND METHODS OF USE TANGO THERAPEUTICS INC (US) 2026-03-19 US disclosed
US-12304907-B2 Compounds and methods of use TANGO THERAPEUTICS, INC. (US) 2025-05-20 US disclosed
US-12264154-B2 Compounds and methods of use TANGO THERAPEUTICS, INC. (US) 2025-04-01 US disclosed
CN-119613233-A Eutectic compound, preparation method and application thereof 上海科胜药物研发有限公司 2025-03-14 CN disclosed
US-5530015-A Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-06-25 US disclosed
CN-1108642-A Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use inproduct of said dihalopropene compounds SUMITOMO CHEMICAL CO (JP) 1995-09-20 CN disclosed
EP-0648729-A1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP disclosed
JP-H061746-A PRODUCTION OF PHENANTHRENE DERIVATIVE AND DIOXOPHENANTHRENE DERIVATIVE OTSUKA PHARMACEUT FACTORY INC 1994-01-11 JP disclosed
US-4943666-A Process for producing nitrophenol compound TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1990-07-24 US disclosed
EP-0339956-A1 Process for producing nitrophenol compound Takeda Chemical Industries, Ltd. (JP) 1989-11-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11584724-B2 Process for synthesis of a phenoxy diaminopyrimidine compound DPYD, DCTPP1, CTDSP1 GABRA1 3237/4885GABRB1 3348/4885ALOX15 4614/4885
US-20210122717-A1 NOVEL PROCESS FOR SYNTHESIS OF A PHENOXY DIAMINOPYRIMIDINE COMPOUND DCTPP1, DPYD, CTDSP1 GABRA1 3146/4885GABRB1 3147/4885ALOX15 4764/4885
US-12264154-B2 Compounds and methods of use F12, C1R, ABCG2 GABRA1 1744/4885GABRB1 1936/4885ALOX15 2070/4885
US-12304907-B2 Compounds and methods of use F12, C1R, ABCG2 GABRA1 1744/4885GABRB1 1936/4885ALOX15 2070/4885
US-20260078117-A1 COMPOUNDS AND METHODS OF USE NR3C2, ADRA1A, CNR1 GABRA1 581/4885GABRB1 727/4885ALOX15 922/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.