Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11582307 | 0.75 | LMNA (0.52) | LTA4HALOX5PPARGPPARAMAOA | |
| SCHEMBL20901322 | 0.71 | ALDH1A1 (0.43) | CYP2D6CTSLCTSBCTSK | |
| SCHEMBL6809826 | 0.71 | MAOA (0.61) | MAOAPTGS1MTNR1AMTNR1BLMNA | |
| SCHEMBL6809832 | 0.71 | MAOA (0.61) | MAOAPTGS1MTNR1AMTNR1BLMNA | |
| SCHEMBL4913490 | 0.71 | ALDH1A1 (0.54) | LTA4HALOX5PPARGPPARAMAOA | |
| SCHEMBL28051598 | 0.71 | ADH1B (0.42) | LMNACTSK | |
| SCHEMBL6683927 | 0.70 | LMNA (0.53) | LTA4HALOX5PPARGPPARAMAOA | |
| SCHEMBL15029217 | 0.70 | LMNA (0.53) | LTA4HALOX5PPARGPPARAMAOA | |
| SCHEMBL7090983 | 0.69 | ALOX5 (0.43) | LTA4HALOX5PPARGPPARAMTNR1A | |
| SCHEMBL1496573 | 0.68 | LMNA (0.56) | LTA4HLMNACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105408304-A | 1,2-disubstituted cyclobutyl compounds | ESTEVE LABOR DR | 2016-03-16 | — | — | CN | disclosed |