Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.65 |
| ▸ | ALDH2 | P05091 | 3/20 | 0.65 |
| ▸ | ALDH3A1 | P30838 | 3/20 | 0.65 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | TP53 | P04637 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.51 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28053364 | 0.85 | ACHE (1.00) | ACHEALDH1A1ALDH2ALDH3A1HSP90AA1 | |
| SCHEMBL578250 | 0.85 | ACHE (0.74) | ACHEALDH1A1ALDH2ALDH3A1HSP90AA1 | |
| SCHEMBL28074704 | 0.84 | CA1 (0.68) | ACHEALDH1A1ALDH2ALDH3A1HSP90AA1 | |
| SCHEMBL18974295 | 0.83 | CHRM1 (0.71) | ACHEALDH1A1ALDH2ALDH3A1MAPT | |
| SCHEMBL16329852 | 0.82 | ACHE (0.83) | ACHEALDH1A1ALDH2ALDH3A1HSP90AA1 | |
| SCHEMBL18954581 | 0.81 | CA1 (0.75) | ACHEALDH1A1ALDH2ALDH3A1CA1 | |
| SCHEMBL5659265 | 0.79 | ALDH1A1 (1.00) | ACHEALDH1A1ALDH2ALDH3A1CHRM5 | |
| SCHEMBL18974299 | 0.78 | ALDH1A1 (0.69) | ACHEALDH1A1ALDH2ALDH3A1MAPT | |
| SCHEMBL4597228 | 0.78 | ACHE (0.77) | ACHEALDH1A1ALDH2ALDH3A1HSP90AA1 | |
| SCHEMBL28070700 | 0.77 | ACHE (0.66) | ACHEALDH1A1ALDH2ALDH3A1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105237521-B | A kind of cumarin-isatin type compound and its preparation method and purposes | 诸暨市志缇生物科技有限公司 | 2018-08-24 | — | — | CN | disclosed |
| CN-105237521-A | Coumarin-isatin type compounds, and preparation method and purpose thereof | UNIV JISHOU | 2016-01-13 | — | — | CN | disclosed |