Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.68 |
| ▸ | CA2 | P00918 | 2/20 | 0.68 |
| ▸ | CA9 | Q16790 | 2/20 | 0.68 |
| ▸ | ACHE | P22303 | 2/20 | 0.62 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | UBE2N | P61088 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | ALDH3A1 | P30838 | 3/20 | 0.54 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.53 |
| ▸ | PARK7 | Q99497 | 2/20 | 0.52 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9094274 | 0.85 | ALDH1A1 (0.62) | CA1CA2CA9HSP90AA1MAPT | |
| SCHEMBL22410741 | 0.85 | ACHE (0.75) | CA1CA2CA9ACHEHSP90AA1 | |
| SCHEMBL578250 | 0.85 | ACHE (0.74) | CA1CA2CA9ACHEHSP90AA1 | |
| SCHEMBL28053291 | 0.84 | ACHE (0.74) | CA1CA2CA9ACHEHSP90AA1 | |
| SCHEMBL13627923 | 0.84 | UBE2N (0.52) | CA1CA2CA9ACHEHSP90AA1 | |
| SCHEMBL18974298 | 0.83 | ALDH1A1 (0.73) | CA1CA2CA9ACHETP53 | |
| SCHEMBL16329852 | 0.82 | ACHE (0.83) | CA1CA2CA9ACHEHSP90AA1 | |
| SCHEMBL18954644 | 0.81 | CA1 (0.78) | CA1CA2CA9UBE2NTDP1 | |
| SCHEMBL578265 | 0.79 | PARK7 (0.74) | CA1CA2CA9ALDH1A1ALDH3A1 | |
| SCHEMBL18974299 | 0.78 | ALDH1A1 (0.69) | CA1CA9ACHETP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105732476-A | Carbazole-isatin type compound and preparation method and application thereof | 吉首大学 | 2016-07-06 | — | — | CN | disclosed |