Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 5/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 5/20 | 0.40 |
| ▸ | PDK3 | Q15120 | 5/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CCR2 | P41597 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28090565 | 0.84 | LMNA (0.49) | POLBPDK1PDK2PDK3PDK4 | |
| SCHEMBL28060867 | 0.82 | PDK1 (0.39) | POLBPDK1PDK2PDK3PDK4 | |
| SCHEMBL28060869 | 0.81 | PDK1 (0.43) | POLBPDK1PDK2PDK3PDK4 | |
| SCHEMBL28832949 | 0.78 | PDK1 (0.51) | PDK1PDK2PDK3PDK4MEN1 | |
| SCHEMBL28070054 | 0.75 | P2RX7 (0.43) | POLBMAPK1LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL29991642 | 0.73 | RXFP1 (0.46) | POLBPDK1PDK2PDK3PDK4 | |
| SCHEMBL12517737 | 0.73 | RXFP1 (0.46) | POLBPDK1PDK2PDK3PDK4 | |
| SCHEMBL28876956 | 0.72 | POLB (0.49) | POLBMEN1KMT2AMAPK1LMNA | |
| SCHEMBL28090478 | 0.71 | PDK1 (0.46) | PDK1PDK2PDK3PDK4MEN1 | |
| SCHEMBL28044065 | 0.71 | HDAC1 (0.42) | MAPK1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103896921-B | As compound and the composition of kinases inhibitor | IRM LLC (BM) | 2016-02-24 | — | — | CN | disclosed |