Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | PELP1 | Q8IZL8 | 1/20 | 0.42 |
| ▸ | MYC | P01106 | 2/20 | 0.40 |
| ▸ | MAX | P61244 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16952275 | 0.81 | MAPT (0.57) | L3MBTL1MAPTALDH1A1TDP1KMT2A | |
| SCHEMBL423843 | 0.79 | ALDH1A1 (0.56) | L3MBTL1MAPTALDH1A1TDP1LMNA | |
| SCHEMBL28003323 | 0.78 | AKR1C3 (0.49) | MAPTALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL7174351 | 0.75 | HSPB1 (0.46) | L3MBTL1MAPTALDH1A1TDP1KMT2A | |
| SCHEMBL28078625 | 0.75 | PDK1 (0.47) | L3MBTL1MAPTALDH1A1TDP1KMT2A | |
| SCHEMBL28017613 | 0.73 | MAPT (0.40) | MAPTALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL22025631 | 0.72 | MAPT (0.47) | L3MBTL1MAPTALDH1A1TDP1KMT2A | |
| SCHEMBL27914911 | 0.72 | TSHR (0.38) | L3MBTL1MAPTALDH1A1TDP1KMT2A | |
| SCHEMBL10582384 | 0.71 | RAB9A (0.54) | L3MBTL1MAPTALDH1A1TDP1KMT2A | |
| SCHEMBL11592413 | 0.71 | ALDH1A1 (0.39) | L3MBTL1MAPTALDH1A1TDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103664845-B | The preparation method of amino-2, the 3-Dihydrobenzofuranes-4-formic acid of a kind of Plk kinase inhibitor drug intermediate 7- | HUNAN OUYA BIOLOGICAL Co.,Ltd. (CN) | 2016-02-10 | — | — | CN | disclosed |