Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | PRKDC | P78527 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL317535 | 0.85 | ALDH1A1 (0.56) | ALDH1A1TDP1LMNAL3MBTL1MAPT | |
| SCHEMBL11224598 | 0.81 | CHEK1 (0.61) | ALDH1A1TDP1LMNASIRT6L3MBTL1 | |
| SCHEMBL28078625 | 0.81 | PDK1 (0.47) | ALDH1A1TDP1LMNASIRT6L3MBTL1 | |
| SCHEMBL16952275 | 0.81 | MAPT (0.57) | ALDH1A1TDP1LMNAL3MBTL1MAPT | |
| SCHEMBL11592413 | 0.80 | ALDH1A1 (0.39) | ALDH1A1TDP1LMNASIRT6L3MBTL1 | |
| SCHEMBL8977874 | 0.79 | HTT (0.68) | ALDH1A1TDP1LMNASIRT6L3MBTL1 | |
| SCHEMBL425259 | 0.79 | TSHR (0.62) | ALDH1A1TDP1LMNASIRT6L3MBTL1 | |
| SCHEMBL30686627 | 0.79 | ALDH1A1 (0.58) | ALDH1A1TDP1LMNASIRT6L3MBTL1 | |
| SCHEMBL4142866 | 0.79 | ALDH1A1 (0.58) | ALDH1A1TDP1LMNASIRT6L3MBTL1 | |
| SCHEMBL28053828 | 0.79 | L3MBTL1 (0.43) | ALDH1A1TDP1LMNAL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11834383-B2 | Energetic feedstock for additive manufacturing | LYNNTECH, INC. (US) | 2023-12-05 | — | — | US | claimed |
| US-20210276931-A1 | Energetic Feedstock for Additive Manufacturing | LYNNTECH, INC. | 2021-09-09 | — | — | US | claimed |
| JP-4331889-B2 | — | — | 2009-09-16 | — | — | JP | claimed |
| EP-1028721-B1 | N,N'-BIS(SULFONYL)HYDRAZINES USEFUL AS ANTINEOPLASTIC AGENTS | UNIV YALE (US) | 2003-06-04 | — | — | EP | claimed |
| JP-2001521893-A | — | — | 2001-11-13 | — | — | JP | claimed |
| EP-1028721-A4 | N,N'-BIS(SULFONYL)HYDRAZINES USEFUL AS ANTINEOPLASTIC AGENTS | UNIV YALE (US) | 2001-01-31 | — | — | EP | claimed |
| EP-1028721-A1 | $i(N,N')-BIS(SULFONYL)HYDRAZINES USEFUL AS ANTINEOPLASTIC AGENTS | Yale University (US) | 2000-08-23 | — | — | EP | claimed |
| US-6040338-A | N,n-bis(sulfonyl)hydrazines useful as antineoplastic agents | YALE UNIVERSITY (US) | 2000-03-21 | — | — | US | claimed |
| WO-1999022726-A1 | N,N'-BIS(SULFONYL)HYDRAZINES USEFUL AS ANTINEOPLASTIC AGENTS | YALE UNIVERSITY (US) | 1999-05-14 | — | — | WO | claimed |
| US-11834383-B2 | Energetic feedstock for additive manufacturing | LYNNTECH, INC. (US) | 2023-12-05 | — | — | US | disclosed |
| US-20210276931-A1 | Energetic Feedstock for Additive Manufacturing | LYNNTECH, INC. | 2021-09-09 | — | — | US | disclosed |
| WO-2019025153-A1 | USE OF SUBSTITUTED N-SULFONYL-N'-ARYL DIAMINOALKANES AND N-SULFONYL-N'-HETEROARYL DIAMINOALKANES OR SALTS THEREOF FOR INCREASING THE STRESS TOLERANCE IN PLANTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-02-07 | — | — | WO | disclosed |
| US-10065926-B2 | Use of substituted dihydrooxindolylsulfonamides, or the salts thereof, for increasing the stress tolerance of plants | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-09-04 | — | — | US | disclosed |
| US-20180199575-A1 | SUBSTITUTED OXOTETRAHYDROQUINOLINYLPHOSPHINIC ACID AND PHOSPHINIC ACID AMIDES OR SALTS THEREOF AND USE THEREOF TO INCREASE STRESS TOLERANCE IN PLANTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-07-19 | — | — | US | disclosed |
| CN-1342145-A | fused ring compound and pharmaceutical use thereof | JAPAN TOBACCO INC (JP) | 2002-03-27 | — | — | CN | disclosed |
| EP-1162196-A1 | FUSED-RING COMPOUNDS AND USE THEREOF AS DRUGS | JAPAN TOBACCO INC. (JP) | 2001-12-12 | — | — | EP | disclosed |
| EP-1028721-A4 | N,N'-BIS(SULFONYL)HYDRAZINES USEFUL AS ANTINEOPLASTIC AGENTS | UNIV YALE (US) | 2001-01-31 | — | — | EP | disclosed |
| EP-1028721-A1 | $i(N,N')-BIS(SULFONYL)HYDRAZINES USEFUL AS ANTINEOPLASTIC AGENTS | Yale University (US) | 2000-08-23 | — | — | EP | disclosed |
| US-6040338-A | N,n-bis(sulfonyl)hydrazines useful as antineoplastic agents | YALE UNIVERSITY (US) | 2000-03-21 | — | — | US | disclosed |
| WO-1999022726-A1 | N,N'-BIS(SULFONYL)HYDRAZINES USEFUL AS ANTINEOPLASTIC AGENTS | YALE UNIVERSITY (US) | 1999-05-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10065926-B2 | Use of substituted dihydrooxindolylsulfonamides, or the salts thereof, for increasing the stress tolerance of plants | SQOR, DHPS, QDPR | ALDH1A1 652/4885TDP1 2264/4885LMNA 4818/4885 |
| US-20180199575-A1 | SUBSTITUTED OXOTETRAHYDROQUINOLINYLPHOSPHINIC ACID AND PHOSPHINIC ACID AMIDES OR SALTS THEREOF AND USE THEREOF TO INCREASE STRESS TOLERANCE IN PLANTS | PPA1, PHOSPHO1, PIP4K2C | ALDH1A1 3502/4885TDP1 2789/4885LMNA 4862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.