Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 3/20 | 0.47 |
| ▸ | TK1 | P04183 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.43 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.43 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.43 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | TK2 | O00142 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Floxuridine SCHEMBL407748 | 0.84 | LMNA (0.68) | TK1LMNASMN1; SMN2ALOX12ADRA1A | |
| Doxribtimine SCHEMBL28210016 | 0.84 | TK1 (0.52) | TK1LMNASMN1; SMN2TK2TSHR | |
| Deoxyuridine SCHEMBL8012707 | 0.83 | DUT (0.47) | DUTTK1LMNASMN1; SMN2SLC28A1 | |
| Deoxyuridine SCHEMBL889540 | 0.82 | DUT (0.64) | DUTTK1LMNASMN1; SMN2SLC28A1 | |
| Deoxyuridine SCHEMBL391224 | 0.82 | DUT (0.64) | DUTTK1LMNASMN1; SMN2SLC28A1 | |
| Deoxyuridine SCHEMBL24512520 | 0.82 | DUT (0.64) | DUTTK1LMNASMN1; SMN2SLC28A1 | |
| Deoxyuridine SCHEMBL2641582 | 0.82 | DUT (0.64) | DUTTK1LMNASMN1; SMN2SLC28A1 | |
| Deoxyuridine SCHEMBL4847464 | 0.82 | DUT (0.64) | DUTTK1LMNASMN1; SMN2SLC28A1 | |
| Deoxyuridine SCHEMBL9219261 | 0.82 | DUT (0.64) | DUTTK1LMNASMN1; SMN2SLC28A1 | |
| Deoxyuridine SCHEMBL19841232 | 0.82 | DUT (0.64) | DUTTK1LMNASMN1; SMN2SLC28A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105287617-A | Application of hypoxanthine, hypoxanthine riboside, xanthine, xanthosine or any combination thereof in preparation of medicines for treating tumors | CUI XIULING | 2016-02-03 | — | — | CN | disclosed |