Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.39 |
| ▸ | MEN1 | O00255 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28949869 | 0.87 | EPHX1 (0.43) | KMT2AMEN1L3MBTL3HSD11B1POLB | |
| SCHEMBL28056859 | 0.84 | FDFT1 (0.47) | KMT2AMEN1LMNAGAA | |
| SCHEMBL5556528 | 0.83 | MAPT (0.47) | KMT2ATHRBNAMPTGPR119KDM4E | |
| SCHEMBL28056726 | 0.82 | NPC1 (0.41) | KMT2AMEN1LMNAL3MBTL3MAPT | |
| SCHEMBL28056784 | 0.81 | PARP10 (0.46) | L3MBTL3POLBGAA | |
| SCHEMBL28056844 | 0.78 | LMNA (0.45) | KMT2ALMNAGPR119MAPT | |
| SCHEMBL10922111 | 0.75 | QDPR (0.40) | POLBKDM4E | |
| SCHEMBL1028407 | 0.73 | NPC1 (0.32) | POLB | |
| SCHEMBL1898647 | 0.72 | — | — | |
| SCHEMBL28166840 | 0.72 | PDE4B (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103732589-B | Can be used as the sulphonamide of the replacement of anti-apoptotic BCL inhibitor | BRISTOL-MYERS SQUIBB CO. (US) | 2016-03-30 | — | — | CN | disclosed |