Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 6/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TGM2 | P21980 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28056859 | 0.85 | FDFT1 (0.47) | LMNAKMT2ATDP1RAB9ASMN1; SMN2 | |
| SCHEMBL28949869 | 0.81 | EPHX1 (0.43) | KMT2AALDH1A1HPGD | |
| SCHEMBL28056726 | 0.81 | NPC1 (0.41) | LMNAKMT2ARAB9ANPC1MAPT | |
| SCHEMBL28056837 | 0.78 | ABL1 (0.40) | LMNAKMT2AMAPTGPR119 | |
| SCHEMBL28056784 | 0.77 | PARP10 (0.46) | TDP1RAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL17360240 | 0.74 | KMT2A (0.55) | LMNAKMT2ASLC6A2SLC6A3TDP1 | |
| SCHEMBL28056725 | 0.73 | HPGD (0.60) | LMNAKMT2ASLC6A2SLC6A3TDP1 | |
| SCHEMBL1028407 | 0.73 | NPC1 (0.32) | RAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL312287 | 0.69 | KMT2A (0.92) | LMNAKMT2ASLC6A2SLC6A3TDP1 | |
| SCHEMBL10922111 | 0.69 | QDPR (0.40) | SLC6A3ALDH1A1CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103732589-B | Can be used as the sulphonamide of the replacement of anti-apoptotic BCL inhibitor | BRISTOL-MYERS SQUIBB CO. (US) | 2016-03-30 | — | — | CN | disclosed |