SCHEMBL28057808

SCHEMBL28057808

O=C(CC(=O)OC(O)c1ccccc1)OC(O)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.45
MAPK1 P28482 1/20 0.45
KMT2A Q03164 1/20 0.44
BCAT2 O15382 1/20 0.43
CRHBP P24387 1/20 0.42
CRHR2 Q13324 1/20 0.42
KDM4E B2RXH2 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
CYP2D6 P10635 2/20 0.41
SRC P12931 1/20 0.41
HDAC3 O15379 1/20 0.41
HDAC4 P56524 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC7 Q8WUI4 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC10 Q969S8 1/20 0.41
HDAC11 Q96DB2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2295734 0.92 LMNA (0.42) LMNAMAPK1KMT2ABCAT2CRHBP
SCHEMBL27751084 0.84 LMNA (0.45) LMNAMAPK1KMT2AKDM4ETSHR
SCHEMBL11588080 0.84 GABBR2 (0.43) LMNAMAPK1BCAT2SMN1; SMN2CYP2D6
SCHEMBL11588773 0.83 CRHBP (0.44) LMNAMAPK1KMT2ABCAT2CRHBP
SCHEMBL9875296 0.81 CRHBP (0.60) LMNAMAPK1KMT2ACRHBPCRHR2
SCHEMBL5613926 0.80 HDAC4 (0.44) LMNAKMT2AL3MBTL1CYP2D6HDAC4
SCHEMBL5932263 0.78 LMNA (0.48) LMNAMAPK1KMT2AL3MBTL1SMN1; SMN2
SCHEMBL3883004 0.78 HCAR2 (0.56) KMT2AKDM4ETSHR
SCHEMBL5062426 0.77 ALDH1A1 (0.56) LMNAMAPK1KMT2ACYP2D6SRC
SCHEMBL5933696 0.77 LMNA (0.46) LMNAMAPK1KMT2AL3MBTL1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108495888-A Additive mixture for stabilizing polyols and polyurethanes 巴斯夫欧洲公司 2018-09-04 CN disclosed
CN-105636954-A Triazine, piperidine and pyrrolidinyl hindered amine light stabilizers BASF SE 2016-06-01 CN disclosed
CN-103003050-B Apparatus and method for producing products from pigment-containing polymer mixtures BAYER INTELLECTUAL PROPERTY GMBH (DE) 2016-02-24 CN disclosed