Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 11/20 | 0.55 |
| ▸ | CA1 | P00915 | 10/20 | 0.55 |
| ▸ | CA12 | O43570 | 3/20 | 0.50 |
| ▸ | CA9 | Q16790 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1422207 | 0.81 | ALDH1A1 (0.63) | GAAALDH1A1POLBL3MBTL1 | |
| SCHEMBL1421898 | 0.80 | HPGD (0.65) | GAAALDH1A1POLBL3MBTL1 | |
| SCHEMBL15956967 | 0.79 | CA1 (0.53) | CA2CA1CA12CA9 | |
| SCHEMBL5205017 | 0.77 | HDAC1 (0.75) | GAAALDH1A1POLBMEN1KMT2A | |
| SCHEMBL19177180 | 0.77 | MAPK1 (0.57) | GAAALDH1A1POLBCA2CA1 | |
| SCHEMBL27884380 | 0.77 | KMT2A (0.61) | GAAALDH1A1POLBCA2CA1 | |
| SCHEMBL8120226 | 0.76 | CA1 (0.57) | CA2CA1CA12CA9 | |
| SCHEMBL559891 | 0.76 | CA2 (0.56) | GAAALDH1A1POLBCA2MEN1 | |
| SCHEMBL5452372 | 0.76 | GAA (0.51) | GAAALDH1A1POLBMEN1KMT2A | |
| SCHEMBL1422100 | 0.76 | HPGD (0.66) | GAAALDH1A1POLBCA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110143999-A | Have cytotoxicity and antimitotic compound and its application method | 酵活有限公司 | 2019-08-20 | — | — | CN | disclosed |
| CN-105358174-B | Cytotoxic and antimitotic compounds and methods of use thereof | 酵活有限公司 | 2019-03-15 | — | — | CN | disclosed |
| CN-106459162-A | VAR2CSA-drug conjugates | 酵活有限公司 | 2017-02-22 | — | — | CN | disclosed |
| CN-105358174-A | Cytotoxic and antimitotic compounds and methods of use thereof | CT FOR DRUG RES AND DEV | 2016-02-24 | — | — | CN | disclosed |