SCHEMBL559891

SCHEMBL559891

NNc1ccc(CC(=O)O)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.56
CAMK2A Q9UQM7 1/20 0.56
MEN1 O00255 2/20 0.55
KMT2A Q03164 2/20 0.55
AKR1B1 P15121 1/20 0.54
GAA P10253 2/20 0.52
ABCC4 O15439 1/20 0.52
LMNA P02545 1/20 0.52
TSHR P16473 1/20 0.52
PTGS1 P23219 1/20 0.52
HTT P42858 1/20 0.52
FFAR1 O14842 3/20 0.51
KDM4E B2RXH2 2/20 0.50
POLB P06746 1/20 0.50
NR1H4 Q96RI1 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
HSD17B10 Q99714 2/20 0.49
ALDH1A1 P00352 2/20 0.47
TP53 P04637 1/20 0.47
RAB9A P51151 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL2064788 0.98 CA2 (0.54) CA2CAMK2AMEN1KMT2AAKR1B1
Hydrochloric Acid SCHEMBL7997252 0.98 CA2 (0.54) CA2CAMK2AMEN1KMT2AAKR1B1
SCHEMBL5272351 0.84 GAA (0.42) CA2CAMK2AMEN1KMT2AGAA
SCHEMBL10717729 0.83 CA2 (0.59) CA2GAAHTTKDM4E
Hydrochloric Acid SCHEMBL10719008 0.81 CA2 (0.57) CA2GAAHTTKDM4E
SCHEMBL69614 0.81 CA2 (0.79) CA2CAMK2AMEN1KMT2AAKR1B1
SCHEMBL14852040 0.80 CA2 (0.58) CA2CAMK2AMEN1KMT2AAKR1B1
SCHEMBL13849278 0.79 MEN1 (0.61) CA2CAMK2AMEN1KMT2AGAA
SCHEMBL3131825 0.79 FFAR1 (0.59) CA2FFAR1NR1H4ALDH1A1
SCHEMBL10457090 0.78 MEN1 (0.65) CA2CAMK2AMEN1KMT2AAKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250066348-A1 SMALL MOLECULE INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 1 (USP1) AND USES THEREOF INSILICO MEDICINE IP LIMITED (HK) 2025-02-27 US disclosed
CN-119173515-A Small molecule inhibitors of ubiquitin-specific protease 1 (USP 1) and uses thereof 英矽智能科技知识产权有限公司 2024-12-20 CN disclosed
EP-4430049-A1 SMALL MOLECULE INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 1 (USP1) AND USES THEREOF Insilico Medicine IP Limited (HK) 2024-09-18 EP disclosed
EP-3309552-B1 DYE COMPOUND SFC CO LTD (KR) 2024-01-17 EP disclosed
WO-2023083285-A1 SMALL MOLECULE INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 1 (USP1) AND USES THEREOF INSILICO MEDICINE IP LIMITED (CN) 2023-05-19 WO disclosed
US-10473666-B2 Dye compounds SFC CO., LTD. (KR) 2019-11-12 US disclosed
US-20180203015-A1 DYE COMPOUNDS SFC CO., LTD. (KR) 2018-07-19 US disclosed
US-20180203015-A1 DYE COMPOUNDS SFC CO., LTD. (KR) 2018-07-19 US disclosed
US-20180179233-A1 NEAR-IR GLUCOSE SENSORS PROFUSA, INC. (US) 2018-06-28 US disclosed
EP-3309552-A1 DYE COMPOUND SFC Co., Ltd. (KR) 2018-04-18 EP disclosed
EP-0971901-A1 PHTHALAZINONES Byk Gulden Lomberg Chemische Fabrik GmbH (DE) 2000-01-19 EP disclosed
WO-1999031181-A1 RIGIDIZED TRIMETHINE CYANINE DYES CARNEGIE MELLON UNIVERSITY (US) 1999-06-24 WO disclosed
WO-1998031674-A1 PHTHALAZINONES BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 1998-07-23 WO disclosed
EP-0438230-B1 Indole-substituted five-membered heteroaromatic compounds MERCK SHARP & DOHME (GB) 1997-04-23 EP disclosed
CN-1143960-A Therapeutic heterocyclic compounds WELLCOME FOUND (GB) 1997-02-26 CN disclosed
EP-0438230-A2 Indole-substituted five-membered heteroaromatic compounds MERCK SHARP & DOHME LTD. (GB) 1991-07-24 EP disclosed
US-4981977-A Intermediate for and fluorescent cyanine dyes containing carboxylic acid groups CARNEGIE-MELLON UNIVERSITY (US) 1991-01-01 US disclosed
US-4285699-A REDOX SYSTEMS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-08-25 US disclosed
US-4278748-A Absorbed hydrazide nucleating agents and photographic elements containing such agents EASTMAN KODAK COMPANY (US) 1981-07-14 US disclosed
US-4239901-A ANALGESICS, ANTIPYRETICS, ANTIINFLAMMATORY AGENTS BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 1980-12-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180179233-A1 NEAR-IR GLUCOSE SENSORS IRS1, INSR, SLC2A4 CA2 935/4885CAMK2A 1732/4885MEN1 3439/4885
US-20250066348-A1 SMALL MOLECULE INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 1 (USP1) AND USES THEREOF USP1, USP2, USP28 CA2 4071/4885CAMK2A 1719/4885MEN1 2224/4885
US-10473666-B2 Dye compounds SQOR, MT-ND5, MT-ND2 CA2 231/4885CAMK2A 2502/4885MEN1 1243/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.