Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7179286 | 0.84 | CES2 (0.41) | CYP2C19SLC1A3SLC1A2SLC1A1ALOX5 | |
| SCHEMBL27878861 | 0.79 | ALOX5 (0.41) | CYP2C19ALOX5CES2CES1KEAP1 | |
| SCHEMBL2880798 | 0.77 | ALOX5 (0.39) | CYP2C19ALOX5CES2CES1KEAP1 | |
| SCHEMBL10340979 | 0.76 | ALOX5 (0.41) | CYP2C19ALOX5CES2CES1KEAP1 | |
| SCHEMBL2071309 | 0.75 | CYP2C19 (0.46) | CYP2C19ALOX5CES2CES1KEAP1 | |
| SCHEMBL12392847 | 0.75 | CYP1A2 (0.47) | SLC1A3SLC1A2SLC1A1CYP1A2MEN1 | |
| SCHEMBL9130249 | 0.74 | ALOX5 (0.39) | CYP2C19ALOX5CES2CES1KEAP1 | |
| SCHEMBL28785571 | 0.74 | LMNA (0.35) | ALOX5CES2CES1KEAP1MEN1 | |
| SCHEMBL14777613 | 0.73 | ALOX5 (0.36) | ALOX5CES2CES1KEAP1ALDH1A1 | |
| SCHEMBL2400082 | 0.72 | CYP2C19 (0.66) | CYP2C19SLC1A3SLC1A2SLC1A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105461987-A | Intercalation kaolinite modified natural rubber material and preparation method thereof | HEFEI JIEMING NEW MATERIAL TECH CO LTD | 2016-04-06 | — | — | CN | claimed |
| CN-105461987-A | Intercalation kaolinite modified natural rubber material and preparation method thereof | HEFEI JIEMING NEW MATERIAL TECH CO LTD | 2016-04-06 | — | — | CN | disclosed |