SCHEMBL28059983

SCHEMBL28059983

CC(C)c1cnc(C(N)=O)c(C(C)C)n1

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 2/20 0.35
ADORA1 P30542 2/20 0.35
PLAU P00749 2/20 0.33
SYK P43405 7/20 0.33
DGAT1 O75907 2/20 0.33
SOAT1 P35610 1/20 0.33
KCNH2 Q12809 2/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28119175 0.73 ADORA3 (0.36) ADORA2AADORA1SYKKCNH2ALDH1A1
SCHEMBL31046830 0.73 ADORA3 (0.36) ADORA2AADORA1SYKKCNH2ALDH1A1
SCHEMBL12796013 0.72 NOS3 (0.31)
SCHEMBL1591438 0.69 NNMT (0.39)
SCHEMBL12848428 0.69 NOS3 (0.33)
SCHEMBL2628913 0.68 SIRT6 (0.52) ALDH1A1LMNA
SCHEMBL27870238 0.68 IKBKE (0.39) PLAU
SCHEMBL31636273 0.67 ADORA3 (0.42) ADORA2AADORA1DGAT1SOAT1KCNH2
SCHEMBL19151634 0.67 ADORA3 (0.42) ADORA2AADORA1DGAT1SOAT1KCNH2
Trifluoroacetic Acid SCHEMBL30045250 0.66 L3MBTL1 (0.38) ADORA2AADORA1SYKKCNH2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105578879-A Composition comprising harmful arthropod-attracting substance formed from plant-derived components and analogs thereof KYOYU AGRI COMPANY LTD 2016-05-11 CN disclosed