Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29705870 | 0.97 | ALDH1A1 (0.36) | ALDH1A1LMNAMAPTKCNJ1PKM | |
| SCHEMBL5612633 | 0.77 | GPR84 (0.39) | ALDH1A1LMNAMAPTKCNJ1PKM | |
| SCHEMBL30721382 | 0.76 | HRH1 (0.39) | ALDH1A1LMNAMAPTKCNJ1PKM | |
| SCHEMBL8529384 | 0.71 | PKM (0.34) | ALDH1A1LMNAMAPTKCNJ1PKM | |
| SCHEMBL4724991 | 0.70 | CAPN1 (0.36) | ALDH1A1LMNAMAPTKCNJ1PKM | |
| SCHEMBL29774334 | 0.69 | APP (0.31) | — | |
| SCHEMBL28514373 | 0.69 | APP (0.31) | — | |
| SCHEMBL7844356 | 0.69 | CYP2D6 (0.36) | ALDH1A1LMNAMAPTPKM | |
| SCHEMBL28060818 | 0.69 | KDM4E (0.31) | ALDH1A1 | |
| SCHEMBL4019485 | 0.68 | TBXAS1 (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115650948-B | Preparation method of glycolide-lactide | 中国科学院长春应用化学研究所 | 2023-12-19 | — | — | CN | claimed |
| CN-115650948-A | Preparation method of glycolide-lactide | 中国科学院长春应用化学研究所 | 2023-01-31 | — | — | CN | claimed |
| CN-115650948-B | Preparation method of glycolide-lactide | 中国科学院长春应用化学研究所 | 2023-12-19 | — | — | CN | disclosed |
| CN-115650948-A | Preparation method of glycolide-lactide | 中国科学院长春应用化学研究所 | 2023-01-31 | — | — | CN | disclosed |