Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | PTGIR | P43119 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28061510 | 0.81 | F2RL1 (0.51) | PTGS1PTGS2AKR1B1PTGDR2ALDH1A1 | |
| SCHEMBL27986845 | 0.78 | NPBWR1 (0.41) | ARTUBB1FFAR4ALDH1A1TUBB4A | |
| SCHEMBL28061534 | 0.78 | PTGIR (0.41) | PTGS1PTGS2AKR1B1PTGDR2AR | |
| SCHEMBL911097 | 0.75 | TAAR1 (0.55) | TUBB1ALDH1A1HTTTUBB4ATUBB | |
| SCHEMBL28061528 | 0.74 | RAPGEF4 (0.67) | GAAFFAR4ALDH1A1GABRG2GABRB3 | |
| SCHEMBL27916620 | 0.73 | PTGS1 (0.39) | PTGS1PTGS2AKR1B1PTGDR2AR | |
| SCHEMBL28061520 | 0.73 | TUBB1 (0.45) | PTGS1PTGS2AKR1B1PTGDR2AR | |
| SCHEMBL28091556 | 0.73 | FFAR4 (0.36) | TUBB1FFAR4ALDH1A1MAPTTUBB4A | |
| SCHEMBL18723690 | 0.72 | TDP1 (0.47) | PTGS1PTGS2AKR1B1PTGDR2AR | |
| SCHEMBL27898744 | 0.72 | PTGS1 (0.39) | PTGS1PTGS2AKR1B1PTGDR2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103038231-B | Modulators of HEC1 activity and methods thereof | Taivex Therapeutics Corp. (CN) | 2016-04-20 | — | — | CN | disclosed |