Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 4/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 2/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18723690 | 0.78 | TDP1 (0.47) | PTGIRPTGS1PTGS2AKR1B1PTGDR2 | |
| SCHEMBL28061531 | 0.78 | PTGS1 (0.38) | PTGIRPTGS1PTGS2AKR1B1PTGDR2 | |
| SCHEMBL28061510 | 0.78 | F2RL1 (0.51) | PTGS1PTGS2AKR1B1PTGDR2MEN1 | |
| SCHEMBL18723868 | 0.77 | PTGS1 (0.39) | PTGIRPTGS1PTGS2AKR1B1PTGDR2 | |
| SCHEMBL28061520 | 0.75 | TUBB1 (0.45) | PTGIRPTGS1PTGS2AKR1B1PTGDR2 | |
| SCHEMBL28091688 | 0.75 | NPBWR1 (0.42) | ARMEN1KMT2AFFAR4ALDH1A1 | |
| SCHEMBL18723828 | 0.73 | PTGS1 (0.41) | PTGIRPTGS1PTGS2AKR1B1PTGDR2 | |
| SCHEMBL28061523 | 0.73 | ALDH1A1 (0.46) | PTGIRPTGS1PTGS2AKR1B1PTGDR2 | |
| SCHEMBL130044 | 0.70 | IDO1 (0.58) | MAOBALDH1A1TP53CYP3A4ALOX15 | |
| SCHEMBL27916620 | 0.70 | PTGS1 (0.39) | PTGIRPTGS1PTGS2AKR1B1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105906617-B | Modulators of HEC1 activity and methods thereof | 泰纬生命科技股份有限公司 | 2018-09-04 | — | — | CN | disclosed |
| CN-105906617-A | Modulators of HEC1 activity and methods thereof | 泰纬生命科技股份有限公司 | 2016-08-31 | — | — | CN | disclosed |
| CN-103038231-B | Modulators of HEC1 activity and methods thereof | Taivex Therapeutics Corp. (CN) | 2016-04-20 | — | — | CN | disclosed |