Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 6/20 | 0.53 |
| ▸ | PARP15 | Q460N3 | 5/20 | 0.53 |
| ▸ | CHEK2 | O96017 | 9/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.37 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.36 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28064086 | 0.89 | LTA4H (0.39) | PARP10PARP15LTA4HTEAD1TEAD3 | |
| SCHEMBL28064060 | 0.89 | LTA4H (0.39) | PARP10PARP15CHEK2HRH3LTA4H | |
| SCHEMBL28064084 | 0.88 | TEAD1 (0.47) | PARP10PARP15LTA4HTEAD1TEAD3 | |
| SCHEMBL28064087 | 0.87 | TEAD1 (0.44) | PARP10PARP15HRH3LTA4HTEAD1 | |
| SCHEMBL28064070 | 0.86 | LTA4H (0.39) | PARP10PARP15HRH3LTA4HTEAD1 | |
| SCHEMBL28064069 | 0.83 | PPARG (0.37) | CHEK2HRH3LTA4HTEAD1TEAD3 | |
| SCHEMBL28064165 | 0.82 | CHEK2 (0.42) | PARP10PARP15CHEK2PARP2HRH3 | |
| SCHEMBL2230054 | 0.81 | PARP15 (0.58) | PARP10PARP15CHEK2PARP2TEAD1 | |
| SCHEMBL28064128 | 0.81 | TEAD1 (0.40) | TEAD1TEAD3 | |
| SCHEMBL28088222 | 0.81 | PPARG (0.37) | PARP10PARP15CHEK2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102803258-B | Alkyl-heterocyclic carbamate derivatives, their preparation and therapeutic use | SAI NUOFEI (FR) | 2016-04-20 | — | — | CN | claimed |
| CN-105837565-A | ALKYL-HETEROCYCLE CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | 赛诺菲 | 2016-08-10 | — | — | CN | disclosed |
| CN-102803258-B | Alkyl-heterocyclic carbamate derivatives, their preparation and therapeutic use | SAI NUOFEI (FR) | 2016-04-20 | — | — | CN | disclosed |