Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 9/20 | 0.42 |
| ▸ | HRH2 | P25021 | 2/20 | 0.42 |
| ▸ | HRH1 | P35367 | 2/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 5/20 | 0.40 |
| ▸ | PARP15 | Q460N3 | 4/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28064074 | 0.88 | ALDH1A1 (0.42) | HRH2HRH1LTA4H | |
| SCHEMBL28064059 | 0.86 | HRH3 (0.39) | HRH2HRH1HRH3ACKR3LTA4H | |
| SCHEMBL28064161 | 0.84 | HCRTR1 (0.42) | CHEK2 | |
| SCHEMBL28064061 | 0.82 | PPARG (0.37) | CHEK2HRH2HRH1ACKR3 | |
| SCHEMBL28064068 | 0.82 | PARP10 (0.53) | CHEK2PARP10PARP15PARP2HRH3 | |
| SCHEMBL2227687 | 0.81 | CHEK2 (0.47) | CHEK2HRH2HRH1PARP10PARP15 | |
| SCHEMBL28064064 | 0.80 | TEAD1 (0.41) | — | |
| SCHEMBL28064076 | 0.77 | PPARG (0.47) | — | |
| SCHEMBL28064167 | 0.77 | KCNA5 (0.46) | — | |
| SCHEMBL28064164 | 0.77 | SIGMAR1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102803258-B | Alkyl-heterocyclic carbamate derivatives, their preparation and therapeutic use | SAI NUOFEI (FR) | 2016-04-20 | — | — | CN | claimed |
| CN-105837565-A | ALKYL-HETEROCYCLE CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | 赛诺菲 | 2016-08-10 | — | — | CN | disclosed |
| CN-102803258-B | Alkyl-heterocyclic carbamate derivatives, their preparation and therapeutic use | SAI NUOFEI (FR) | 2016-04-20 | — | — | CN | disclosed |