Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.35 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28064060 | 0.88 | LTA4H (0.39) | LTA4HHRH3PARP15PARP10TEAD1 | |
| SCHEMBL28064086 | 0.88 | LTA4H (0.39) | LTA4HPARP15PARP10TEAD1TEAD3 | |
| SCHEMBL28064084 | 0.88 | TEAD1 (0.47) | LTA4HPARP15PARP10TEAD1TEAD3 | |
| SCHEMBL28064087 | 0.86 | TEAD1 (0.44) | LTA4HHRH3PARP15PARP10TEAD1 | |
| SCHEMBL28064068 | 0.86 | PARP10 (0.53) | LTA4HHRH3CTSSPARP15PARP10 | |
| SCHEMBL28064081 | 0.84 | PTGDR2 (0.40) | KCNH2CYP2C9 | |
| SCHEMBL28064059 | 0.82 | HRH3 (0.39) | LTA4HHRH3KCNH2TEAD1TEAD3 | |
| SCHEMBL28064080 | 0.82 | HRH3 (0.39) | LTA4HHRH3KCNH2CTSSTEAD1 | |
| SCHEMBL28064069 | 0.82 | PPARG (0.37) | LTA4HHRH3KCNH2TEAD1TEAD3 | |
| SCHEMBL2227965 | 0.81 | CHRM4 (0.42) | LTA4HHRH3KCNH2CTSSPARP15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102803258-B | Alkyl-heterocyclic carbamate derivatives, their preparation and therapeutic use | SAI NUOFEI (FR) | 2016-04-20 | — | — | CN | claimed |
| CN-105837565-A | ALKYL-HETEROCYCLE CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | 赛诺菲 | 2016-08-10 | — | — | CN | disclosed |
| CN-102803258-B | Alkyl-heterocyclic carbamate derivatives, their preparation and therapeutic use | SAI NUOFEI (FR) | 2016-04-20 | — | — | CN | disclosed |