Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.37 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28064060 | 0.90 | LTA4H (0.39) | LTA4HPARP15PARP10TEAD1TEAD3 | |
| SCHEMBL28064084 | 0.90 | TEAD1 (0.47) | LTA4HPARP15PARP10TEAD1TEAD3 | |
| SCHEMBL28064087 | 0.89 | TEAD1 (0.44) | LTA4HPARP15PARP10TEAD1TEAD3 | |
| SCHEMBL28064068 | 0.89 | PARP10 (0.53) | LTA4HPARP15PARP10TEAD1TEAD3 | |
| SCHEMBL28064070 | 0.88 | LTA4H (0.39) | LTA4HPARP15PARP10TEAD1TEAD3 | |
| SCHEMBL28064295 | 0.86 | HCRTR1 (0.36) | LTA4HPARP15PARP10MAPTSMN1; SMN2 | |
| SCHEMBL28088153 | 0.85 | HRH3 (0.37) | MAPTSMN1; SMN2RORCMEN1KMT2A | |
| SCHEMBL28064069 | 0.84 | PPARG (0.37) | LTA4HTEAD1TEAD3 | |
| SCHEMBL28064102 | 0.83 | KDM4E (0.41) | TEAD1TEAD3MEN1KMT2A | |
| SCHEMBL28827928 | 0.82 | MEN1 (0.39) | LTA4HTEAD1TEAD3MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102803258-B | Alkyl-heterocyclic carbamate derivatives, their preparation and therapeutic use | SAI NUOFEI (FR) | 2016-04-20 | — | — | CN | claimed |
| CN-105837565-A | ALKYL-HETEROCYCLE CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | 赛诺菲 | 2016-08-10 | — | — | CN | disclosed |
| CN-102803258-B | Alkyl-heterocyclic carbamate derivatives, their preparation and therapeutic use | SAI NUOFEI (FR) | 2016-04-20 | — | — | CN | disclosed |