Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD1 | P28347 | 1/20 | 0.44 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28064084 | 0.96 | TEAD1 (0.47) | TEAD1TEAD3LTA4HPARP15PARP10 | |
| SCHEMBL28064128 | 0.94 | TEAD1 (0.40) | TEAD1TEAD3CSF1RKDRFAAH | |
| SCHEMBL28064086 | 0.89 | LTA4H (0.39) | TEAD1TEAD3LTA4HPARP15PARP10 | |
| SCHEMBL28064060 | 0.89 | LTA4H (0.39) | TEAD1TEAD3LTA4HHRH3PARP15 | |
| SCHEMBL28064068 | 0.87 | PARP10 (0.53) | TEAD1TEAD3LTA4HHRH3PARP15 | |
| SCHEMBL28064070 | 0.86 | LTA4H (0.39) | TEAD1TEAD3LTA4HHRH3PARP15 | |
| SCHEMBL28064102 | 0.83 | KDM4E (0.41) | TEAD1TEAD3 | |
| SCHEMBL28064069 | 0.83 | PPARG (0.37) | TEAD1TEAD3LTA4HHRH3 | |
| SCHEMBL28064078 | 0.82 | TEAD1 (0.45) | TEAD1TEAD3LTA4HCSF1RKDR | |
| SCHEMBL2228411 | 0.81 | TEAD1 (0.49) | TEAD1TEAD3CSF1RKDRFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102803258-B | Alkyl-heterocyclic carbamate derivatives, their preparation and therapeutic use | SAI NUOFEI (FR) | 2016-04-20 | — | — | CN | claimed |
| CN-105837565-A | ALKYL-HETEROCYCLE CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | 赛诺菲 | 2016-08-10 | — | — | CN | disclosed |
| CN-102803258-B | Alkyl-heterocyclic carbamate derivatives, their preparation and therapeutic use | SAI NUOFEI (FR) | 2016-04-20 | — | — | CN | disclosed |