Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 3/20 | 0.38 |
| ▸ | PPARD | Q03181 | 3/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.37 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28064086 | 0.90 | LTA4H (0.39) | LTA4HPARP15PARP10KMT2AMEN1 | |
| SCHEMBL28064069 | 0.90 | PPARG (0.37) | LTA4HPPARGPPARDHRH3CHEK2 | |
| SCHEMBL28064084 | 0.90 | TEAD1 (0.47) | LTA4HPPARGPPARDLMNAPPARA | |
| SCHEMBL28064087 | 0.89 | TEAD1 (0.44) | LTA4HHRH3PARP15PARP10TEAD1 | |
| SCHEMBL28064068 | 0.89 | PARP10 (0.53) | LTA4HHRH3CHEK2PARP15PARP10 | |
| SCHEMBL28064070 | 0.88 | LTA4H (0.39) | LTA4HHRH3PARP15PARP10HPGD | |
| SCHEMBL28064203 | 0.87 | PPARG (0.46) | PPARGPPARDPPARAGRM5 | |
| SCHEMBL28088222 | 0.84 | PPARG (0.37) | PPARGPPARDHRH3CHEK2LMNA | |
| SCHEMBL28064163 | 0.83 | ALDH1A1 (0.38) | PPARGPPARDPPARAHPGDKMT2A | |
| SCHEMBL28064062 | 0.81 | RAB9A (0.39) | LTA4HPPARGPPARDHRH3CHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102803258-B | Alkyl-heterocyclic carbamate derivatives, their preparation and therapeutic use | SAI NUOFEI (FR) | 2016-04-20 | — | — | CN | claimed |
| CN-105837565-A | ALKYL-HETEROCYCLE CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | 赛诺菲 | 2016-08-10 | — | — | CN | disclosed |