Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | HRH2 | P25021 | 2/20 | 0.36 |
| ▸ | HRH1 | P35367 | 2/20 | 0.36 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.36 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28064074 | 0.87 | ALDH1A1 (0.42) | LTA4HHRH2HRH1TEAD1TEAD3 | |
| SCHEMBL28064165 | 0.86 | CHEK2 (0.42) | HRH3LTA4HHRH2HRH1ACKR3 | |
| SCHEMBL28064161 | 0.83 | HCRTR1 (0.42) | HCRTR2POLBHPGD | |
| SCHEMBL28064070 | 0.82 | LTA4H (0.39) | HRH3KCNH2LTA4HTEAD1TEAD3 | |
| SCHEMBL28064061 | 0.82 | PPARG (0.37) | KCNH2HRH2HRH1TEAD1TEAD3 | |
| SCHEMBL28064080 | 0.81 | HRH3 (0.39) | HRH3KCNH2LTA4HTEAD1TEAD3 | |
| SCHEMBL2227417 | 0.81 | GRIN2B (0.44) | HRH3KCNH2LTA4HHRH2HRH1 | |
| SCHEMBL28064064 | 0.80 | TEAD1 (0.41) | HCRTR2TEAD1TEAD3MEN1KMT2A | |
| SCHEMBL28064167 | 0.77 | KCNA5 (0.46) | MEN1KMT2AHPGD | |
| SCHEMBL28064164 | 0.77 | SIGMAR1 (0.38) | MEN1KMT2AGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102803258-B | Alkyl-heterocyclic carbamate derivatives, their preparation and therapeutic use | SAI NUOFEI (FR) | 2016-04-20 | — | — | CN | claimed |
| CN-105837565-A | ALKYL-HETEROCYCLE CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | 赛诺菲 | 2016-08-10 | — | — | CN | disclosed |