SCHEMBL28064110

SCHEMBL28064110

CC(C)(C)[Si](C)(C)OCCCCC(Cc1cc2cc(Br)ccc2[nH]1)OC=O

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DUT P33316 1/20 0.33
IDO1 P14902 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14745993 0.75 IDO1 (0.39) DUTIDO1
SCHEMBL27738751 0.74 FLT3 (0.39) IDO1
SCHEMBL27782152 0.72 PYGL (0.35) IDO1
SCHEMBL9539675 0.65 DUT (0.40) DUT
SCHEMBL28064107 0.65 DUT (0.37) DUTIDO1
SCHEMBL14745382 0.65 NOS1 (0.34) DUTIDO1
SCHEMBL27633289 0.64 CYP2A6 (0.41)
SCHEMBL27919843 0.64 KDM4E (0.38) IDO1
SCHEMBL19360498 0.64 CYP2A6 (0.37) DUT
SCHEMBL27650372 0.64 CYP19A1 (0.39) IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103347875-B As the indoles of respiratory syncytial virus antiviral agent JANSSEN R&D IRELAND (IE) 2016-03-30 CN disclosed