SCHEMBL28065851

SCHEMBL28065851

c1cc(-c2cc[nH]n2)c[nH]1

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP19A1 P11511 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
PPARA Q07869 1/20 0.30
IDO1 P14902 1/20 0.30
KDR P35968 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16766999 0.78 LMNA (0.36) CYP1A2IDO1
SCHEMBL28313237 0.75
SCHEMBL1673128 0.74
SCHEMBL9438 0.71 CYP1A2 (0.48) CYP1A2IDO1
SCHEMBL28029443 0.71 AKT2 (0.54)
SCHEMBL16670417 0.71 PDE3B (0.39) CYP1A2CYP2C9CYP2C19
SCHEMBL31748352 0.71 ALDH1A1 (0.37)
SCHEMBL3691479 0.71 CYP1A2 (0.46) CYP1A2CYP3A4CYP2D6CYP19A1CYP2C9
SCHEMBL2148569 0.70 IDO1 (0.48) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL842040 0.70 CYP1A2 (0.47) CYP1A2IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113754649-A Indole derivatives containing oxadiazole, triazole and pyrazole structural units and application thereof 贵州大学 2021-12-07 CN disclosed
CN-105682461-B Pesticidal combination and relative method 美国陶氏益农公司 2019-06-14 CN disclosed
CN-105682461-A Pesticidal compositions and related methods 美国陶氏益农公司 2016-06-15 CN disclosed