Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDE | P14735 | 2/20 | 0.42 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28068051 | 0.92 | IDE (0.41) | IDEHTR6TSHRPIK3C3PDE4A | |
| SCHEMBL28068083 | 0.89 | IDE (0.43) | IDEHTR6TSHRPIK3C3PDE4A | |
| SCHEMBL28068045 | 0.89 | HTR6 (0.42) | IDEHTR6NAMPTALDH1A1CHRNB4 | |
| SCHEMBL19971349 | 0.84 | IDE (0.40) | IDEHTR6TSHRPDE4APDE4B | |
| SCHEMBL16619409 | 0.80 | HTR6 (0.44) | IDEHTR6PDE4APDE4BPDE4C | |
| SCHEMBL28207563 | 0.80 | IDE (0.42) | IDEHTR6 | |
| SCHEMBL28068106 | 0.78 | HTR6 (0.39) | IDEHTR6TSHRALDH1A1 | |
| SCHEMBL16626635 | 0.78 | HTR6 (0.38) | IDEHTR6PDE4APDE4BPDE4C | |
| SCHEMBL28068112 | 0.78 | HTR6 (0.46) | HTR6CHRNB4CHRNA3 | |
| SCHEMBL16618718 | 0.77 | PDE4A (0.43) | IDEHTR6PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105612150-A | Sulfonylindole derivatives and process for producing the same | DAE WOONG PHARMA | 2016-05-25 | — | — | CN | claimed |
| CN-105612150-B | Sulfonylindole derivatives and process for producing the same | 株式会社大熊制药 | 2018-04-10 | — | — | CN | disclosed |
| CN-105612150-A | Sulfonylindole derivatives and process for producing the same | DAE WOONG PHARMA | 2016-05-25 | — | — | CN | disclosed |