Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDE | P14735 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 5/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | PLK1 | P53350 | 1/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19971357 | 0.92 | IDE (0.39) | IDENAMPTPDE4APDE4BPDE4C | |
| SCHEMBL19971346 | 0.90 | IDE (0.41) | IDENAMPTPDE4APDE4BPDE4C | |
| SCHEMBL19971352 | 0.86 | PDE4A (0.42) | IDENAMPTPDE4APDE4BPDE4C | |
| SCHEMBL28068056 | 0.84 | IDE (0.42) | IDENAMPTPDE4APDE4BPDE4C | |
| SCHEMBL19971359 | 0.84 | HTR6 (0.42) | IDEHTR6CHRNB4CHRNA3 | |
| SCHEMBL28207563 | 0.81 | IDE (0.42) | IDEHTR6 | |
| SCHEMBL19971356 | 0.80 | IDE (0.37) | IDENAMPTPDE4APDE4BPDE4C | |
| SCHEMBL16619409 | 0.80 | HTR6 (0.44) | IDENAMPTPDE4APDE4BPDE4C | |
| SCHEMBL2472672 | 0.79 | NAMPT (0.43) | IDENAMPTTSHRHTTCHRNB4 | |
| SCHEMBL28068106 | 0.77 | HTR6 (0.39) | IDEHTR6ATMTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | claimed |
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |