Trifluoromethylbenzene

Trifluoromethylbenzene

SCHEMBL28068069

CC(=NO)c1ccccc1.FC(F)(F)c1ccccc1

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.54
TSHR P16473 1/20 0.54
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
PPARG P37231 1/20 0.42
PPARA Q07869 1/20 0.42
KIF11 P52732 1/20 0.42
CA9 Q16790 1/20 0.41
MAPT P10636 2/20 0.41
GAA P10253 1/20 0.41
LMNA P02545 2/20 0.40
TRPV6 Q9H1D0 1/20 0.40
MAPK1 P28482 1/20 0.40
HTT P42858 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
CES2 O00748 1/20 0.40
NR4A1 P22736 1/20 0.40
NR4A2 P43354 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4022029 0.86 CES2 (0.50) ALDH1A1RAB9ACA9LMNACES2
SCHEMBL266456 0.86 CES2 (0.50) ALDH1A1RAB9ACA9LMNACES2
SCHEMBL2736631 0.83 LMNA (0.52) ALDH1A1NPC1RAB9APPARGPPARA
SCHEMBL45278 0.83 LMNA (0.52) ALDH1A1NPC1RAB9APPARGPPARA
Benzene SCHEMBL28280701 0.83 LMNA (0.52) ALDH1A1NPC1RAB9APPARGPPARA
SCHEMBL257242 0.83 LMNA (0.52) ALDH1A1NPC1RAB9APPARGPPARA
SCHEMBL3628848 0.83 KMT2A (0.62) ALDH1A1MEN1KMT2AMAPTGAA
SCHEMBL30112938 0.83 KMT2A (0.62) ALDH1A1MEN1KMT2AMAPTGAA
SCHEMBL7797181 0.83 KMT2A (0.62) ALDH1A1MEN1KMT2AMAPTGAA
SCHEMBL11620296 0.83 CA9 (0.44) ALDH1A1TSHRMEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107864960-A A kind of benzoic acid system herbicide and its collocation method 安徽省益农化工有限公司 2018-04-03 CN disclosed
CN-103787916-B A kind of preparation method of trifloxystrobin 京博农化科技股份有限公司 2016-07-13 CN disclosed