SCHEMBL3628848

SCHEMBL3628848

CC(=NO)c1cccc(C(F)(F)F)c1

nearest known ligand 0.62

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.62
MEN1 O00255 2/20 0.62
GAA P10253 1/20 0.57
CES2 O00748 2/20 0.56
NPSR1 Q6W5P4 3/20 0.49
SRD5A2 P31213 1/20 0.47
ALDH1A1 P00352 3/20 0.47
MAPT P10636 1/20 0.47
HTT P42858 1/20 0.47
POLB P06746 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7797181 1.00 KMT2A (0.62) KMT2AMEN1GAACES2NPSR1
SCHEMBL30112938 1.00 KMT2A (0.62) KMT2AMEN1GAACES2NPSR1
SCHEMBL15295774 1.00 KMT2A (0.62) KMT2AMEN1GAACES2NPSR1
SCHEMBL17899795 0.85 KMT2A (0.62) KMT2AMEN1GAACES2NPSR1
SCHEMBL7255041 0.84 KMT2A (0.60) KMT2AMEN1GAACES2NPSR1
SCHEMBL15597554 0.84 MEN1 (0.45) KMT2AMEN1GAACES2NPSR1
SCHEMBL7255042 0.84 KMT2A (0.60) KMT2AMEN1GAACES2NPSR1
Trifluoromethylbenzene SCHEMBL28068069 0.83 ALDH1A1 (0.54) KMT2AMEN1GAACES2ALDH1A1
SCHEMBL8274363 0.83 ACHE (0.51) KMT2AMEN1GAANPSR1HTT
SCHEMBL14088920 0.83 ACHE (0.51) KMT2AMEN1GAANPSR1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 201 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120040314-A Method for continuously preparing m-trifluoromethyl acetophenone oxime 山东师范大学实验厂有限公司 2025-05-27 CN claimed
CN-116589379-B Post-treatment process of m-trifluoromethyl acetophenone oxime 河北诚信集团有限公司 2025-04-01 CN claimed
CN-119431183-A Process for continuously synthesizing m-trifluoromethyl acetophenone oxime by adopting microchannel reactor 中国计量大学 2025-02-14 CN claimed
CN-118993932-A Efficient clean synthesis method of m-trifluoromethyl acetophenone oxime 辽宁众辉生物科技有限公司 2024-11-22 CN claimed
CN-115043754-B Clean synthesis method of trifloxystrobin 辽宁众辉生物科技有限公司 2024-09-20 CN claimed
EP-3681863-B1 \"AN IMPROVED PROCESS FOR THE PREPARATION OF TRIFLOXYSTROBIN\ HIKAL LTD (IN) 2024-07-17 EP claimed
CN-117886715-A Green and efficient synthesis method of m-trifluoromethyl acetophenone oxime 山东京博农化科技股份有限公司 2024-04-16 CN claimed
CN-117820163-A Synthesis method of trifloxystrobin 山东华阳农药化工集团有限公司 2024-04-05 CN claimed
CN-114685313-B Preparation method of trifloxystrobin 江西天宇化工有限公司 2024-04-05 CN claimed
WO-2023223105-A1 A PROCESS OF PREPARATION OF 3'-(TRIFLUOROMETHYL)ACETOPHENONE (TFMAP) DEEPAK NITRITE LIMITED (IN) 2023-11-23 WO claimed
CN-112538029-A Green synthesis method for preparing trifloxystrobin with high yield 利民化学有限责任公司 2021-03-23 CN claimed
US-20200283373-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF TRIFLOXYSTROBIN HIKAL LIMITED (IN) 2020-09-10 US claimed
CN-111333535-A Preparation method of trifloxystrobin 江苏食品药品职业技术学院 2020-06-26 CN claimed
CN-101941921-A Method for preparing trifloxystrobin YUEYANG DIPU CHEMICAL TECHNOLOGY CO LTD 2011-01-12 CN claimed
CN-100357263-C Preparation process of oxime strain ester UNIV TONGJI (CN) 2007-12-26 CN claimed
CN-100334070-C Tech. for synthesizing high productivity oxime kresoxim TONGNA ENVIRONMENT PROT SCI & (CN) 2007-08-29 CN claimed
CN-1303061-C Liquid phase synthesis process of oxime strain ester by poly-ethandiol UNIV TONGJI (CN) 2007-03-07 CN claimed
CN-1793115-A Tech. for synthesizing high productivity oxime kresoxim TONGNA ENVIRONMENT PROT SCI & (CN) 2006-06-28 CN claimed
CN-1560028-A Liquid phase synthesis process of oxime strain ester by poly-ethandiol 同济大学 2005-01-05 CN claimed
CN-1560027-A Preparation process of oxime strain ester 同济大学 2005-01-05 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200283373-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF TRIFLOXYSTROBIN SI, TREH, CYP3A7 KMT2A 3996/4885MEN1 2691/4885GAA 9/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.