SCHEMBL7797181

SCHEMBL7797181

C/C(=N\O)c1cccc(C(F)(F)F)c1

nearest known ligand 0.62

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.62
MEN1 O00255 2/20 0.62
GAA P10253 1/20 0.57
CES2 O00748 2/20 0.56
NPSR1 Q6W5P4 3/20 0.49
SRD5A2 P31213 1/20 0.47
ALDH1A1 P00352 3/20 0.47
MAPT P10636 1/20 0.47
HTT P42858 1/20 0.47
POLB P06746 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30112938 1.00 KMT2A (0.62) KMT2AMEN1GAACES2NPSR1
SCHEMBL3628848 1.00 KMT2A (0.62) KMT2AMEN1GAACES2NPSR1
SCHEMBL15295774 1.00 KMT2A (0.62) KMT2AMEN1GAACES2NPSR1
SCHEMBL17899795 0.85 KMT2A (0.62) KMT2AMEN1GAACES2NPSR1
SCHEMBL7255041 0.84 KMT2A (0.60) KMT2AMEN1GAACES2NPSR1
SCHEMBL15597554 0.84 MEN1 (0.45) KMT2AMEN1GAACES2NPSR1
SCHEMBL7255042 0.84 KMT2A (0.60) KMT2AMEN1GAACES2NPSR1
Trifluoromethylbenzene SCHEMBL28068069 0.83 ALDH1A1 (0.54) KMT2AMEN1GAACES2ALDH1A1
SCHEMBL8274363 0.83 ACHE (0.51) KMT2AMEN1GAANPSR1HTT
SCHEMBL14088920 0.83 ACHE (0.51) KMT2AMEN1GAANPSR1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3681863-B1 \"AN IMPROVED PROCESS FOR THE PREPARATION OF TRIFLOXYSTROBIN\ HIKAL LTD (IN) 2024-07-17 EP claimed
US-11649204-B2 Process for the preparation of trifloxystrobin HIKAL LIMITED (IN) 2023-05-16 US claimed
US-20200283373-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF TRIFLOXYSTROBIN HIKAL LIMITED (IN) 2020-09-10 US claimed
EP-3681863-B1 \"AN IMPROVED PROCESS FOR THE PREPARATION OF TRIFLOXYSTROBIN\ HIKAL LTD (IN) 2024-07-17 EP disclosed
EP-3681863-B1 \"AN IMPROVED PROCESS FOR THE PREPARATION OF TRIFLOXYSTROBIN\ HIKAL LTD (IN) 2024-07-17 EP disclosed
CN-114685313-B Preparation method of trifloxystrobin 江西天宇化工有限公司 2024-04-05 CN disclosed
US-11649204-B2 Process for the preparation of trifloxystrobin HIKAL LIMITED (IN) 2023-05-16 US disclosed
US-11649204-B2 Process for the preparation of trifloxystrobin HIKAL LIMITED (IN) 2023-05-16 US disclosed
US-11649204-B2 Process for the preparation of trifloxystrobin HIKAL LIMITED (IN) 2023-05-16 US disclosed
CN-114685313-A Preparation method of trifloxystrobin 南通泰禾化工股份有限公司 2022-07-01 CN disclosed
CN-108368033-B Method for preparing trifloxystrobin GSP作物科学有限公司 2021-05-04 CN disclosed
WO-2013144924-A1 AN IMPROVED PROCESS FOR THE SYNTHESIS OF STROBILURIN FUNGICIDES VIZ TRIFLOXYSTROBIN AND KRESOXIM-METHYL RALLIS INDIA LTD. (IN) 2013-10-03 WO disclosed
EP-0912499-B1 PESTICIDES BAYER AG (DE) 2001-12-12 EP disclosed
US-6288071-B1 FUNGICIDES, INSECTICIDES, MITICIDES BAYER AKTIENGESELLSCHAFT (DE) 2001-09-11 US disclosed
EP-0912499-A1 PESTICIDES Novartis AG (CH) 1999-05-06 EP disclosed
WO-1999011129-A1 ENANTIOMERICALLY ENRICHED COMPOSITIONS AND THEIR PESTICIDAL USE E.I. DU PONT DE NEMOURS AND COMPANY (US) 1999-03-11 WO disclosed
EP-0874831-A1 PROCESSES AND COMPOUNDS FOR PREPARING CYCLIC UREA FUNGICIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1998-11-04 EP disclosed
WO-1997047592-A1 PESTICIDES NOVARTIS AG (CH) 1997-12-18 WO disclosed
WO-1997019935-A1 PROCESSES AND COMPOUNDS FOR PREPARING CYCLIC UREA FUNGICIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-06-05 WO disclosed
WO-1996036229-A1 FUNGICIDAL CYCLIC AMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-11-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11649204-B2 Process for the preparation of trifloxystrobin CYP3A7, CYP51A1, TREH KMT2A 4049/4885MEN1 3130/4885GAA 22/4885
US-20200283373-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF TRIFLOXYSTROBIN SI, TREH, CYP3A7 KMT2A 3996/4885MEN1 2691/4885GAA 9/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.