Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | IDE | P14735 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.32 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28068106 | 0.85 | HTR6 (0.39) | NAPRTHTR6KDM4EIDEHPGD | |
| SCHEMBL28068088 | 0.82 | HTR6 (0.36) | NAPRTHTR6KDM4EIDEHPGD | |
| SCHEMBL19984047 | 0.80 | HTR6 (0.43) | NAPRTHTR6IDEPDE4APDE4B | |
| SCHEMBL16619076 | 0.77 | HTR6 (0.47) | HTR6IDEHDAC1PDE4APDE4B | |
| SCHEMBL28068083 | 0.76 | IDE (0.43) | HTR6IDEPDE4APDE4BPDE4C | |
| SCHEMBL19971346 | 0.76 | IDE (0.41) | HTR6IDEHDAC1PDE4APDE4B | |
| SCHEMBL19971345 | 0.76 | IDE (0.43) | HTR6IDEPDE4APDE4BPDE4C | |
| SCHEMBL16626645 | 0.72 | HTR6 (0.41) | HTR6IDEHDAC1PDE4APDE4B | |
| SCHEMBL19971360 | 0.71 | AKR1C3 (0.56) | NAPRTHTR6KDM4EIDEHDAC1 | |
| SCHEMBL28658615 | 0.71 | CYP17A1 (0.39) | NAPRTKDM4EHPGDHDAC1CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105612150-A | Sulfonylindole derivatives and process for producing the same | DAE WOONG PHARMA | 2016-05-25 | — | — | CN | disclosed |