Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.54 |
| ▸ | DRD3 | P35462 | 4/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.49 |
| ▸ | HTR3B | O95264 | 1/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | HTR3A | P46098 | 1/20 | 0.49 |
| ▸ | HTR6 | P50406 | 1/20 | 0.49 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.49 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20408268 | 0.84 | HTR7 (0.43) | DRD2MAPTALDH1A1ALOX15 | |
| SCHEMBL456981 | 0.82 | GABRA1 (0.43) | LMNAALDH1A1HPGDALOX15CYP1A2 | |
| Hydrochloric Acid SCHEMBL739371 | 0.81 | GABRA1 (0.41) | LMNAALDH1A1HPGDALOX15CYP1A2 | |
| Hydrochloric Acid SCHEMBL1727636 | 0.79 | DPP4 (0.40) | LMNAALDH1A1HPGDALOX15CYP1A2 | |
| Hydrochloric Acid SCHEMBL1609149 | 0.79 | ADRB1 (0.44) | ADRB1LMNAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL20408269 | 0.77 | FAAH (0.48) | DRD2MAPTALDH1A1ALOX15 | |
| SCHEMBL30720573 | 0.77 | DRD2 (0.66) | DRD2DRD3CYP2C19HTR3EHTR3B | |
| SCHEMBL16834267 | 0.76 | ATM (0.46) | DRD2DRD3CYP2C19HTR3EHTR3B | |
| SCHEMBL16834193 | 0.76 | ATM (0.40) | DRD2DRD3CYP2C19HTR3EHTR3B | |
| SCHEMBL28396037 | 0.76 | DRD2 (0.40) | DRD2DRD3CYP2C19HTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105813742-A | Metal-ligand complex, olefin polymerization catalyst derived therefrom, and olefin polymerization method utilizing the catalyst | 陶氏环球技术有限责任公司 | 2016-07-27 | — | — | CN | disclosed |