Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 6/20 | 0.80 |
| ▸ | MAOB | P27338 | 4/20 | 0.80 |
| ▸ | MGAM | O43451 | 1/20 | 0.80 |
| ▸ | MAOA | P21397 | 1/20 | 0.80 |
| ▸ | XDH | P47989 | 1/20 | 0.80 |
| ▸ | AKT1 | P31749 | 1/20 | 0.76 |
| ▸ | DHODH | Q02127 | 1/20 | 0.62 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Broussochalcone B SCHEMBL1576619 | 1.00 | PTPN1 (0.80) | PTPN1MAOBMGAMMAOAXDH | |
| SCHEMBL19960676 | 0.91 | PTPN1 (0.78) | PTPN1MAOBMGAMMAOAXDH | |
| SCHEMBL26552078 | 0.90 | PTPN1 (0.65) | PTPN1MAOBMGAMMAOAXDH | |
| SCHEMBL26552064 | 0.90 | AKT1 (0.80) | PTPN1MAOBMGAMMAOAXDH | |
| Stipulin SCHEMBL29435847 | 0.90 | PTPN1 (0.88) | PTPN1MAOBMGAMMAOAXDH | |
| Stipulin SCHEMBL633710 | 0.90 | PTPN1 (0.88) | PTPN1MAOBMGAMMAOAXDH | |
| Stipulin SCHEMBL633709 | 0.90 | PTPN1 (0.88) | PTPN1MAOBMGAMMAOAXDH | |
| SCHEMBL31297034 | 0.90 | MAOB (0.67) | PTPN1MAOBMGAMMAOAXDH | |
| Broussochalcone A SCHEMBL431919 | 0.89 | PTPN1 (1.00) | PTPN1MAOBMGAMMAOAXDH | |
| Broussochalcone A SCHEMBL32689658 | 0.89 | PTPN1 (1.00) | PTPN1MAOBMGAMMAOAXDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2683351-B1 | USE OF A 2-METHYLSUCCINIC ACID DIESTER DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS CONTAINING THE SAME | OREAL (FR) | 2019-10-16 | — | — | EP | disclosed |
| US-20160067160-A1 | USE OF A 2-METHYLSUCCINIC ACID DIESTER DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS CONTAINING THE SAME | OREAL (FR) | 2016-03-10 | — | — | US | disclosed |
| US-20150224046-A1 | COMPOSITION CONTAINING A SUPERABSORBENT POLYMER AND AN ORGANIC UV SCREENING AGENT | L'OREAL (FR) | 2015-08-13 | — | — | US | disclosed |
| EP-2482793-B1 | USE OF PIPERIDINE ESTER DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS COMPRISING IT | ORÉAL L (FR) | 2015-04-22 | — | — | EP | disclosed |
| US-8716311-B2 | Use of piperidine ester derivative as solvent in cosmetic compositions; cosmetic compositions comprising it | L'OREAL (FR) | 2014-05-06 | — | — | US | disclosed |
| US-20140056832-A1 | USE OF A 2-METHYLSUCCINIC ACID DIESTER DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS CONTAINING THE SAME | L'OREAL (FR) | 2014-02-27 | — | — | US | disclosed |
| EP-2683351-A2 | USE OF A 2-METHYLSUCCINIC ACID DIESTER DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS CONTAINING THE SAME | L'Oréal (FR) | 2014-01-15 | — | — | EP | disclosed |
| US-20120282197-A1 | USE OF PIPERIDINE ESTER DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS COMPRISING IT | L'OREAL (FR) | 2012-11-08 | — | — | US | disclosed |
| US-20120269746-A1 | USE OF CAPROLACTAM DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS COMPRISING IT | L'OREAL (FR) | 2012-10-25 | — | — | US | disclosed |
| WO-2012119861-A2 | USE OF A 2-METHYLSUCCINIC ACID DIESTER DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS CONTAINING THE SAME | L'OREAL (FR) | 2012-09-13 | — | — | WO | disclosed |
| US-20100330018-A1 | COMPOSITION CONTAINING A SUPERABSORBENT POLYMER AND AN ORGANIC UV SCREENING AGENT | L'OREAL (FR) | 2010-12-30 | — | — | US | disclosed |
| US-20100143276-A1 | Ester solvents derived from 4-carboxy-2-pyrrolidinone formulated into UV-screening cosmetic compositions | L'OREAL (FR) | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140056832-A1 | USE OF A 2-METHYLSUCCINIC ACID DIESTER DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS CONTAINING THE SAME | DIMT1, MAT2A, SCD | PTPN1 4501/4885MAOB 1478/4885MGAM 1334/4885 |
| US-20150224046-A1 | COMPOSITION CONTAINING A SUPERABSORBENT POLYMER AND AN ORGANIC UV SCREENING AGENT | KRT18, FABP2, FABP4 | PTPN1 4313/4885MAOB 1681/4885MGAM 1367/4885 |
| US-20120282197-A1 | USE OF PIPERIDINE ESTER DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS COMPRISING IT | PLD1, PLD2, FFAR1 | PTPN1 4748/4885MAOB 912/4885MGAM 4790/4885 |
| US-20160067160-A1 | USE OF A 2-METHYLSUCCINIC ACID DIESTER DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS CONTAINING THE SAME | DIMT1, FADS2, SCD | PTPN1 4519/4885MAOB 1280/4885MGAM 1233/4885 |
| US-20100330018-A1 | COMPOSITION CONTAINING A SUPERABSORBENT POLYMER AND AN ORGANIC UV SCREENING AGENT | KRT18, FABP2, FABP4 | PTPN1 4313/4885MAOB 1681/4885MGAM 1367/4885 |
| US-20120269746-A1 | USE OF CAPROLACTAM DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS COMPRISING IT | DEGS1, CAPN1, PPT1 | PTPN1 4133/4885MAOB 1060/4885MGAM 3319/4885 |
| US-20100143276-A1 | Ester solvents derived from 4-carboxy-2-pyrrolidinone formulated into UV-screening cosmetic compositions | FASN, ALOX12, PAH | PTPN1 4522/4885MAOB 959/4885MGAM 4710/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.