Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 2/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CCR3 | P51677 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 6/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.44 |
| ▸ | RYR2 | Q92736 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27997754 | 0.87 | CCR3 (0.45) | ADRA1AADRA2AMAPTALOX12L3MBTL1 | |
| SCHEMBL28076611 | 0.83 | MAPT (0.48) | MAPTALOX12L3MBTL1CCR3MEN1 | |
| SCHEMBL28076624 | 0.81 | HTR1A (0.52) | MAPTALOX12L3MBTL1MEN1POLB | |
| SCHEMBL28076620 | 0.81 | HTR1A (0.46) | ADRA1AMAPTALOX12L3MBTL1CCR3 | |
| SCHEMBL28076582 | 0.80 | CYP2D6 (0.55) | ADRA1AMAPTALOX12L3MBTL1HTR1A | |
| SCHEMBL28076704 | 0.78 | GAA (0.56) | ADRA1AMAPTALOX12L3MBTL1CCR3 | |
| SCHEMBL28076801 | 0.77 | HTR1A (0.52) | MAPTALOX12L3MBTL1CCR3HTR1A | |
| SCHEMBL28076769 | 0.77 | HTR1A (0.52) | MAPTALOX12L3MBTL1HTR1ASLC6A4 | |
| SCHEMBL28830809 | 0.77 | DRD4 (0.62) | MAPTMEN1POLBKMT2ADRD4 | |
| SCHEMBL28830757 | 0.77 | TSHR (0.60) | MEN1POLBKMT2ADRD4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103980184-B | Piperidine compounds, medical composition and its use containing this compound | 爱思开生物制药株式会社 | 2016-08-24 | — | — | CN | claimed |