Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 5/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28830757 | 0.90 | TSHR (0.60) | DRD4GAAMEN1KMT2ACACNA1G | |
| SCHEMBL28076585 | 0.87 | DRD4 (0.58) | DRD4MAPTGAAMEN1KMT2A | |
| SCHEMBL27997716 | 0.84 | DRD4 (0.55) | DRD4MAPTGAAMAPK1MEN1 | |
| SCHEMBL14864563 | 0.83 | DRD4 (0.80) | DRD4MAPTGAAMEN1KMT2A | |
| SCHEMBL28076582 | 0.82 | CYP2D6 (0.55) | DRD4MAPTGAACYP2D6 | |
| SCHEMBL28076771 | 0.80 | HTR1A (0.52) | DRD4 | |
| SCHEMBL28076704 | 0.79 | GAA (0.56) | DRD4MAPTGAAMEN1KMT2A | |
| SCHEMBL28076624 | 0.78 | HTR1A (0.52) | DRD4MAPTGAAMEN1KMT2A | |
| SCHEMBL12576638 | 0.77 | DRD4 (0.80) | DRD4MAPTGAAMAPK1MEN1 | |
| SCHEMBL28076611 | 0.77 | MAPT (0.48) | DRD4MAPTGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103980184-B | Piperidine compounds, medical composition and its use containing this compound | 爱思开生物制药株式会社 | 2016-08-24 | — | — | CN | disclosed |