Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.58 |
| ▸ | SPR | P35270 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 8/20 | 0.50 |
| ▸ | NPC1 | O15118 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.47 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.46 |
| ▸ | SCD | O00767 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1856770 | 0.90 | LMNA (0.55) | HSD11B1SPRRAB9ANPC1TP53 | |
| SCHEMBL2720172 | 0.86 | SCD5 (0.49) | HSD11B1SPRNPC1MAPTALDH1A1 | |
| SCHEMBL14413518 | 0.85 | HSD11B1 (0.56) | HSD11B1SPRRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL20149063 | 0.85 | HSD11B1 (0.60) | HSD11B1SPRRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL14276847 | 0.85 | HSD11B1 (0.56) | HSD11B1SPRRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL16600285 | 0.85 | HSD11B1 (0.56) | HSD11B1SPRRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL3183827 | 0.84 | RAB9A (0.67) | HSD11B1SPRRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL3184817 | 0.84 | RAB9A (0.67) | HSD11B1SPRRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL3183837 | 0.84 | RAB9A (0.67) | HSD11B1SPRRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL16565829 | 0.83 | RAB9A (0.67) | HSD11B1SPRRAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100240638-A1 | Organic Compounds and their uses | NOVARTIS AG (CH) | 2010-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240638-A1 | Organic Compounds and their uses | OAT, HAVCR2, CYP3A43 | HSD11B1 269/4885SPR 1305/4885RAB9A 3989/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.