Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | STAT6 | P42226 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.38 |
| ▸ | RELA | Q04206 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28077207 | 0.79 | ALDH1A1 (0.46) | ALDH1A1NPC1RAB9AALOX5MAPT | |
| SCHEMBL13801072 | 0.76 | ALDH1A1 (0.42) | TRPM8ALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL28077336 | 0.76 | HDAC9 (0.39) | TRPM8LMNAALOX5MAPT | |
| SCHEMBL17374828 | 0.75 | TRPM8 (0.55) | TRPM8ALDH1A1MAPTKDM4E | |
| SCHEMBL4297511 | 0.73 | HTR2B (0.42) | TRPM8ALDH1A1HTR2BNPC1RAB9A | |
| SCHEMBL8989405 | 0.73 | TRPM8 (0.36) | TRPM8ALDH1A1HTR2BNPC1RAB9A | |
| SCHEMBL1954805 | 0.72 | ALOX5 (0.56) | TRPM8ALDH1A1ALOX5MEN1KMT2A | |
| SCHEMBL28077372 | 0.71 | SLC9A1 (0.35) | TRPM8ALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL17374836 | 0.71 | TRPM8 (0.79) | TRPM8ALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL23176718 | 0.70 | ALDH1A1 (0.39) | TRPM8ALDH1A1NPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104334544-B | Benzimidazole proline derivative | 埃科特莱茵药品有限公司 | 2016-10-19 | — | — | CN | disclosed |