Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 8/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28077371 | 0.79 | TRPM8 (0.64) | TRPM8 | |
| SCHEMBL28831015 | 0.78 | ALOX5 (0.62) | TRPM8ALOX5 | |
| SCHEMBL13801071 | 0.78 | ADORA3 (0.59) | TRPM8MEN1ALDH1A1KMT2AADORA3 | |
| SCHEMBL1954805 | 0.77 | ALOX5 (0.56) | TRPM8MEN1ALDH1A1KMT2AALOX5 | |
| SCHEMBL28077379 | 0.77 | ALOX5 (0.41) | ALOX5 | |
| SCHEMBL17374826 | 0.76 | TRPM8 (0.74) | TRPM8MEN1KMT2A | |
| SCHEMBL4153015 | 0.75 | KMT2A (0.53) | TRPM8MEN1ALDH1A1KMT2AADORA3 | |
| SCHEMBL28077214 | 0.73 | KMO (0.40) | TRPM8ALOX5 | |
| SCHEMBL12875931 | 0.72 | ALDH1A1 (0.46) | TRPM8MEN1ALDH1A1KMT2AADORA3 | |
| SCHEMBL12875924 | 0.72 | LMNA (0.54) | TRPM8MEN1ALDH1A1KMT2AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104334544-B | Benzimidazole proline derivative | 埃科特莱茵药品有限公司 | 2016-10-19 | — | — | CN | disclosed |