Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28384785 | 0.90 | MGLL (0.51) | NPC1RAB9ATDP1KMT2APOLB | |
| SCHEMBL10904247 | 0.86 | KMT2A (0.53) | L3MBTL1KDM4ETDP1CASP3SENP7 | |
| Hydrochloric Acid SCHEMBL10904248 | 0.84 | KMT2A (0.52) | L3MBTL1KDM4ETDP1CASP3SENP7 | |
| SCHEMBL28079976 | 0.84 | L3MBTL1 (0.56) | NPC1RAB9AL3MBTL1KDM4EGAA | |
| Hydrochloric Acid SCHEMBL10905007 | 0.84 | KMT2A (0.52) | L3MBTL1KDM4ETDP1CASP3SENP7 | |
| SCHEMBL8375337 | 0.83 | KMT2A (0.50) | KDM4ETDP1CASP3SENP7SENP6 | |
| SCHEMBL3492807 | 0.81 | LMNA (0.51) | TDP1KMT2APOLBCYP2D6ALDH1A1 | |
| SCHEMBL14974133 | 0.80 | POLB (0.47) | NPC1RAB9ATDP1KMT2APOLB | |
| SCHEMBL8519008 | 0.80 | NAAA (0.57) | TDP1HPGDKMT2APOLBEPHX1 | |
| SCHEMBL27419910 | 0.79 | ALDH1A1 (0.53) | NPC1RAB9ATDP1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109715146-A | Eradicate the method and composition of leukaemia cell | 哈佛学院校长同事会 | 2019-05-03 | — | — | CN | disclosed |
| CN-102802623-A | Compounds, compositions and methods comprising 1,3,4-oxadiazole derivatives | INST ONEWORLD HEALTH | 2012-11-28 | — | — | CN | disclosed |
| CN-102695510-A | Pyrimido-pyrrolo-quinoxalinedione inhibitors of cystic fibrosis transmembrane conductance regulator protein and uses therefor | UNIV CALIFORNIA | 2012-09-26 | — | — | CN | disclosed |
| CN-102458122-A | Compounds, compositions and methods comprising pyridazine sulfonamide derivatives | INST ONEWORLD HEALTH | 2012-05-16 | — | — | CN | disclosed |
| CN-101668732-A | CFTR inhibitor compound and uses thereof | INST ONEWORLD HEALTH | 2010-03-10 | — | — | CN | disclosed |
| US-20080103205-A1 | Pesticidal compositions and methods of use | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. | 2008-05-01 | — | — | US | disclosed |
| CN-1960966-A | Hydrazide-containing CFTR inhibitor compounds and uses thereof | UNIV CALIFORNIA (US) | 2007-05-09 | — | — | CN | disclosed |
| WO-2007050867-A2 | PESTICIDAL COMPOSITIONS AND METHODS OF USE | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2007-05-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080103205-A1 | Pesticidal compositions and methods of use | SLC47A1, SLC22A8, SLC47A2 | NPC1 717/4885RAB9A 2385/4885L3MBTL1 1466/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.