Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 19/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 17/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 15/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | TSPO | P30536 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Mazaticol SCHEMBL34619 | 0.79 | CHRM3 (0.51) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| Mazaticol SCHEMBL182361 | 0.79 | CHRM3 (0.50) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| Mazaticol SCHEMBL17747972 | 0.78 | CHRM3 (0.50) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| Mazaticol SCHEMBL13724754 | 0.76 | ALDH1A1 (0.36) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| Mazaticol SCHEMBL15229491 | 0.69 | ADRA1A (0.39) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL4886984 | 0.68 | CHRM3 (0.60) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL4886957 | 0.68 | CHRM3 (0.60) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL4886970 | 0.68 | CHRM3 (0.60) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL11929003 | 0.61 | SIGMAR1 (0.40) | CHRM3CHRM2CHRM1CHRM4TMEM97 | |
| SCHEMBL16742011 | 0.61 | CHRM3 (0.60) | CHRM3CHRM2CHRM1CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103717597-B | Heterocyclic compounds as kinase inhibitors | 原真股份有限公司 | 2017-07-04 | — | — | CN | disclosed |
| CN-103492389-B | Pyrazolo [4,3-d] pyrimidine as inhibitors of kinases | 原真股份有限公司 | 2016-09-14 | — | — | CN | disclosed |