SCHEMBL28465210

SCHEMBL28465210

Cc1cc(C)c(C(=O)Oc2ccccc2)c(N(Cc2ccccc2)Cc2ccccc2)c1

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NR3C1 P04150 5/20 0.42
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
ATM Q13315 1/20 0.42
TSPO P30536 3/20 0.42
MMP1 P03956 2/20 0.40
MMP13 P45452 2/20 0.40
MMP9 P14780 1/20 0.40
RAB9A P51151 2/20 0.39
NPC1 O15118 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
CYP2C19 P33261 1/20 0.39
MAPT P10636 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
TRPM8 Q7Z2W7 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28471123 0.82 MAPT (0.44) NR3C1TSPOMMP1MMP13MMP9
SCHEMBL9282972 0.81 MAPT (0.49) MEN1KMT2ARAB9ANPC1SMN1; SMN2
Phosphine SCHEMBL28088577 0.80 MAPT (0.48) MEN1KMT2ARAB9ANPC1SMN1; SMN2
SCHEMBL21771967 0.76 KMT2A (0.47) NR3C1MEN1KMT2AATMTSPO
SCHEMBL9286049 0.76 CYP3A4 (0.55) MEN1KMT2AATMRAB9ANPC1
SCHEMBL113438 0.73 TSPO (0.41) NR3C1KMT2ATSPOMAPTNPSR1
SCHEMBL21771962 0.73 MEN1 (0.46) NR3C1MEN1KMT2AATMTSPO
SCHEMBL1688010 0.71 MEN1 (0.41) NR3C1MEN1KMT2AATMTSPO
SCHEMBL6128436 0.71 NR3C1 (0.39) NR3C1MEN1KMT2AATMTSPO
SCHEMBL21771979 0.71 MEN1 (0.47) NR3C1MEN1KMT2ATSPOSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108517022-B Solid catalyst component for olefin polymerization, catalyst and application thereof 北京利和知信科技有限公司 2020-10-27 CN disclosed
CN-108517021-B Solid catalyst component suitable for producing polymer with wide molecular weight distribution, catalyst and application thereof 北京利和知信科技有限公司 2020-10-27 CN disclosed