Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.31 |
| ▸ | GCGR | P47871 | 2/20 | 0.31 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.31 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.31 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29104498 | 0.82 | ACHE (0.40) | ACHETDP1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL27741071 | 0.79 | LMNA (0.44) | MAOBMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL2922472 | 0.78 | ALDH1A1 (0.35) | NFE2L2PTGS1NPC1 | |
| SCHEMBL27516264 | 0.76 | PTGS2 (0.53) | PTGS1 | |
| SCHEMBL8328581 | 0.75 | MAPK14 (0.41) | KDM4ELMNARAB9AMAPK14GCGR | |
| SCHEMBL10505427 | 0.75 | PTGS1 (0.42) | PTGS1MAOBSMN1; SMN2KDM4EMAPK14 | |
| SCHEMBL28033337 | 0.75 | LOXL2 (0.54) | MAOB | |
| SCHEMBL28776894 | 0.73 | RAB9A (0.41) | ACHEALDH1A3TDP1MEN1KMT2A | |
| SCHEMBL422511 | 0.71 | ACHE (0.81) | ACHENFE2L2PTGS1ALDH1A3MAOB | |
| SCHEMBL20804472 | 0.71 | ACHE (0.81) | ACHENFE2L2PTGS1ALDH1A3MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104926628-B | A kind of synthetic method of benzil analog derivative | 浙江工业大学 | 2016-08-24 | — | — | CN | disclosed |