Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28089793 | 0.85 | ALDH1A1 (0.39) | KDM4EALDH1A1CYP2C19POLBL3MBTL1 | |
| SCHEMBL28089929 | 0.78 | L3MBTL1 (0.57) | KDM4EALDH1A1KMT2ATSHRCYP2C19 | |
| Tert-Butylamine SCHEMBL28089934 | 0.76 | KMT2A (0.58) | KDM4EALDH1A1KMT2APOLBCHRNB2 | |
| SCHEMBL21061654 | 0.70 | ALDH1A1 (0.65) | KDM4EALDH1A1KMT2ACYP2C9POLB | |
| SCHEMBL28089927 | 0.69 | LMNA (0.41) | KDM4EALDH1A1TSHRCYP2C19POLB | |
| SCHEMBL7562507 | 0.68 | CHRM1 (0.51) | KDM4EALDH1A1POLBL3MBTL1 | |
| SCHEMBL7562501 | 0.68 | CHRM1 (0.51) | KDM4EALDH1A1POLBL3MBTL1 | |
| SCHEMBL27577321 | 0.68 | ALDH1A1 (0.70) | KDM4EALDH1A1RIPK1KMT2APOLB | |
| SCHEMBL5798534 | 0.67 | NOTUM (0.59) | KDM4ECYP2C19CHRNB2CHRNA4 | |
| Picolamine SCHEMBL7260671 | 0.67 | ALDH1A1 (0.49) | KDM4EALDH1A1CYP2C9TSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103619838-B | Piperidinyl monocarboxylic acids as S1P1 receptor agonists | 生物计划公司 | 2016-08-24 | — | — | CN | disclosed |