Known targets — ChEMBL curated mechanism
GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQ
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL411461 | 0.92 | — | — | |
| Bromide SCHEMBL1985235 | 0.92 | — | — | |
| Iodide SCHEMBL9805251 | 0.92 | — | — | |
| Bromide SCHEMBL11879388 | 0.88 | TDP1 (0.39) | — | |
| SCHEMBL117185 | 0.85 | TDP1 (0.37) | — | |
| SCHEMBL11439905 | 0.85 | — | — | |
| Nitrous Acid SCHEMBL152437 | 0.79 | ALDH1A1 (0.38) | — | |
| SCHEMBL1650596 | 0.79 | CA4 (0.43) | — | |
| Bicarbonate SCHEMBL2810754 | 0.79 | CA2 (0.50) | — | |
| SCHEMBL5403 | 0.79 | ALDH1A1 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0244055-A2 | Method of sequencing peptides | BIO-AFFINITY SYSTEMS, INC. (US) | 1987-11-04 | — | — | EP | claimed |
| US-4665037-A | Method of sequencing peptides | ANALYTICHEM INTERNATIONAL, INC. (US) | 1987-05-12 | — | — | US | claimed |
| US-4124749-A | Aryl mercury containing polymers | ALLIED CHEMICAL CORPORATION (US) | 1978-11-07 | — | — | US | claimed |
| US-20250262173-A1 | INTRANASAL EPINEPHRINE FORMULATIONS AND METHODS OF USE | RA CAPITAL AGENCY SERVICES, LLC, AS ADMINISTRATIVE AGENT FOR THE SECURED PARTIES | 2025-08-21 | — | — | US | disclosed |
| US-20250262305-A1 | INTRANASAL EPINEPHRINE FORMULATIONS AND METHODS FOR THE TREATMENT OF DISEASE | ARS PHARMACEUTICALS INC. | 2025-08-21 | — | — | US | disclosed |
| US-12324838-B2 | Intranasal epinephrine formulations and methods for the treatment of disease | AEGIS THERAPEUTICS, LLC (US) | 2025-06-10 | — | — | US | disclosed |
| EP-4483958-A2 | INTRANASAL EPINEPHRINE FORMULATIONS AND METHODS FOR THE TREATMENT OF DISEASE | Aegis Therapeutics, LLC (US) | 2025-01-01 | — | — | EP | disclosed |
| US-20240398763-A1 | ORAL DOSAGE FORM CONTAINING ONCOLOGICAL ACTIVE INGREDIENT | OWP Pharmaceuticals, Inc. | 2024-12-05 | — | — | US | disclosed |
| US-20240165191-A1 | COMPOSITIONS AND METHODS FOR REDUCING THE TRANSMISSIVITY OF ILLNESSES USING AN ORAL DELIVERY SYSTEM | LORENZEN LEE H (US) | 2024-05-23 | — | — | US | disclosed |
| US-11918655-B2 | Intranasal epinephrine formulations and methods for the treatment of disease | AEGIS THERAPEUTICS, LLC (US) | 2024-03-05 | — | — | US | disclosed |
| US-20240024485-A1 | INTRANASAL EPINEPHRINE FORMULATIONS AND METHODS FOR THE TREATMENT OF DISEASE | NEF ROYALTY SUB LLC | 2024-01-25 | — | — | US | disclosed |
| US-4482759-A | Fungicidally active benzhydrol derivatives | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1984-11-13 | — | — | US | disclosed |
| US-4324799-A | Fungicidal thioglycolic acid anilides, processes for their manufacture and pesticidal compositions containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-04-13 | — | — | US | disclosed |
| US-4256848-A | Synergistic polyurethane co-catalysts which are a combination of an organo-mercuric compound and a zinc salt of an alkyl carboxylic acid | BASF WYANDOTTE CORPORATION (US) | 1981-03-17 | — | — | US | disclosed |
| US-4124749-A | Aryl mercury containing polymers | ALLIED CHEMICAL CORPORATION (US) | 1978-11-07 | — | — | US | disclosed |
| US-4076930-A | Polysaccharide polyols | ELLINGBOE JAMES | 1978-02-28 | — | — | US | disclosed |
| US-4038490-A | WATER-SEAL SPLICE FOR COAXIAL CABLES AND METHOD OF MAKING SAME | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 1977-07-26 | — | — | US | disclosed |
| US-4026908-A | Catalytic epoxidation process | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1977-05-31 | — | — | US | disclosed |
| US-3993752-A | ALKALI METAL HYDROXIDES AND BORATES; HEAVY METAL SALTS OR OXIDES; FUNGICIDES | KOPPERS COMPANY, INC. (US) | 1976-11-23 | — | — | US | disclosed |
| US-3932509-A | FUNGICIDES, VIRICIDES | CIBA-GEIGY CORPORATION (US) | 1976-01-13 | — | — | US | disclosed |