SCHEMBL1650596

SCHEMBL1650596

[Hg+]c1ccccc1.[O-]B(O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA4 P22748 3/20 0.43
CA14 Q9ULX7 2/20 0.43
ORAI1 Q96D31 2/20 0.43
ORAI2 Q96SN7 2/20 0.43
ORAI3 Q9BRQ5 2/20 0.43
TRPV6 Q9H1D0 2/20 0.43
CA6 P23280 1/20 0.43
CA5A P35218 1/20 0.43
CA7 P43166 1/20 0.43
ENPP2 Q13822 1/20 0.43
CA5B Q9Y2D0 1/20 0.43
PCSK9 Q8NBP7 1/20 0.43
CA1 P00915 6/20 0.36
CA2 P00918 6/20 0.36
MGLL Q99685 2/20 0.36
TDP1 Q9NUW8 2/20 0.35
CA12 O43570 1/20 0.35
GLA P06280 1/20 0.35
CA3 P07451 1/20 0.35
CA9 Q16790 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL117185 0.87 TDP1 (0.37) CA4CA14ORAI1ORAI2ORAI3
Hydrochloric Acid SCHEMBL411461 0.79
Bromide SCHEMBL1985235 0.79
Water SCHEMBL2808996 0.79
Iodide SCHEMBL9805251 0.79
Bromide SCHEMBL11879388 0.76 TDP1 (0.39) CA4CA14CA7CA1CA2
Phenol SCHEMBL31536802 0.75 CA4 (0.43) CA4CA14ORAI1ORAI2ORAI3
Bicarbonate SCHEMBL2810754 0.75 CA2 (0.50) CA4CA14CA6CA5ACA7
SCHEMBL11439905 0.73
SCHEMBL10594453 0.73 CA4 (0.36) CA4CA14CA6CA5ACA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12640053-B2 GYN pathology surgical simulation models and systems for surgical training APPLIED MEDICAL RESOURCES CORPORATION (US) 2026-05-26 US disclosed
US-20260124286-A1 E. COLI FIMH MUTANTS AND USES THEREOF PFIZER INC. (US) 2026-05-07 US disclosed
US-12611201-B2 Absorptive tip brush biopsy device, kit and method TECHMED VENTURES LLC (US) 2026-04-28 US disclosed
EP-4728076-A1 METHOD FOR STABILIZING RNA Pfizer Inc. (US) 2026-04-22 EP disclosed
US-20260102147-A1 BRUSH BIOPSY DEVICE, KIT AND METHOD TECHMED VENTURES LLC (US) 2026-04-16 US disclosed
US-20260077104-A1 Bioelectric Thread and Delivery Device UNIV BROWN (US) 2026-03-19 US disclosed
EP-3515571-B1 ISOTOPIC COMPOSITIONS BOTANICAL WATER TECH IP LTD (GB) 2026-01-07 EP disclosed
US-12508279-B2 Compositions and methods for enhancing innate immunity in a subject for treatment of infections and cancer and other acute and chronic conditions of the eye COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2025-12-30 US disclosed
WO-2025264674-A1 COMPOSITION FOR PERSONAL CARE PRODUCTS VAGINAL BIOME SCIENCE, INC. (US) 2025-12-26 WO disclosed
US-20250381121-A1 COMPOSITION FOR PERSONAL CARE PRODUCTS VAGINAL BIOME SCIENCE INC (US) 2025-12-18 US disclosed
CN-110312492-B Artificial airway management apparatus, systems and methods 因多克里公司 2022-04-08 CN disclosed
US-20220087805-A1 Urinary Plug Device HESSE DAVID (US) 2022-03-24 US disclosed
WO-2022056038-A1 ABSORPTIVE TIP BRUSH BIOPSY DEVICE, KIT AND METHOD TECHMED VENTURES, LLC (US) 2022-03-17 WO disclosed
US-11246693-B2 Urinary plug device HESSE DAVID (US) 2022-02-15 US disclosed
US-9932300-B2 N,N′-diarylurea compounds and N,N′-diarylthiourea compounds as inhibitors of translation initiation PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2018-04-03 US disclosed
US-20160318857-A1 N,N'-Diarylurea Compounds and N,N'-Diarylthiourea Compounds as Inhibitors of Translation Initiation PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2016-11-03 US disclosed
US-9421211-B2 N,N′-diarylurea compounds and N,N′-diarylthiourea compounds as inhibitors of translation initiation PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2016-08-23 US disclosed
US-20120115915-A1 N,N'-DIARYLUREA COMPOUNDS AND N,N'-DIARYLTHIOUREA COMPOUNDS AS INHIBITORS OF TRANSLATION INITIATION PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2012-05-10 US disclosed
US-7927613-B2 Pharmaceutical co-crystal compositions UNIVERSITY OF SOUTH FLORIDA (US) 2011-04-19 US disclosed
US-7790905-B2 Pharmaceutical propylene glycol solvate compositions MCNEIL-PPC, INC. (US) 2010-09-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12508279-B2 Compositions and methods for enhancing innate immunity in a subject for treatment of infections and cancer and other acute and chronic conditions of the eye TLR9, TLR3, TLR6 CA4 3565/4885CA14 2730/4885ORAI1 636/4885
US-20160318857-A1 N,N'-Diarylurea Compounds and N,N'-Diarylthiourea Compounds as Inhibitors of Translation Initiation NSUN2, EIF2AK2, RNGTT CA4 4749/4885CA14 4405/4885ORAI1 3761/4885
US-12640053-B2 GYN pathology surgical simulation models and systems for surgical training CDH1, EPCAM, ZP1 CA4 4398/4885CA14 2280/4885ORAI1 1127/4885
US-20260102147-A1 BRUSH BIOPSY DEVICE, KIT AND METHOD KRT18, PAX2, SETDB1 CA4 2120/4885CA14 481/4885ORAI1 483/4885
US-20260077104-A1 Bioelectric Thread and Delivery Device TNNI3, TNNT2, TTN CA4 4350/4885CA14 4216/4885ORAI1 1128/4885
US-20260124286-A1 E. COLI FIMH MUTANTS AND USES THEREOF Q6ZSR9, MRPL21, F13A1 CA4 3786/4885CA14 2219/4885ORAI1 1993/4885
US-12611201-B2 Absorptive tip brush biopsy device, kit and method PAX8, PAX2, KRT18 CA4 1699/4885CA14 527/4885ORAI1 1370/4885
US-20120115915-A1 N,N'-DIARYLUREA COMPOUNDS AND N,N'-DIARYLTHIOUREA COMPOUNDS AS INHIBITORS OF TRANSLATION INITIATION NSUN2, EIF2AK2, RNGTT CA4 4749/4885CA14 4405/4885ORAI1 3761/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.