Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | RXRA | P19793 | 1/20 | 0.57 |
| ▸ | RXRB | P28702 | 1/20 | 0.57 |
| ▸ | RXRG | P48443 | 1/20 | 0.57 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.54 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.54 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | YAP1 | P46937 | 1/20 | 0.53 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.53 |
| ▸ | ME3 | Q16798 | 1/20 | 0.53 |
| ▸ | FAAH | O00519 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28033057 | 0.90 | ACHE (0.53) | GLAMAPTRXRARXRBRXRG | |
| SCHEMBL28822397 | 0.87 | PTPN1 (0.55) | MAPTPTPN2PTPN1PTPN6FAAH | |
| SCHEMBL28033000 | 0.87 | L3MBTL1 (0.60) | MAPTPTPN2PTPN1PTPN6FAAH | |
| SCHEMBL28033418 | 0.86 | HTT (0.62) | GLAMAPTPTPN2PTPN1PTPN6 | |
| SCHEMBL28264102 | 0.84 | PTPN1 (0.52) | GLAMAPTPTPN2PTPN1PTPN6 | |
| SCHEMBL27710111 | 0.82 | EPHX2 (0.54) | MAPTMEN1KMT2AEPHX2SMN1; SMN2 | |
| SCHEMBL3557554 | 0.81 | PTPN2 (0.81) | GLAMAPTRXRARXRBRXRG | |
| SCHEMBL27613627 | 0.81 | ALDH1A1 (0.48) | MAPTCARM1PRMT6 | |
| Hydrochloric Acid SCHEMBL28768913 | 0.80 | PTPN2 (0.79) | GLAMAPTRXRARXRBRXRG | |
| SCHEMBL3604589 | 0.79 | KMT2A (0.54) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105916841-A | Functionalised and substituted indoles as anti-cancer agents | 诺沃根公司 | 2016-08-31 | — | — | CN | disclosed |